AutismKB 2.0

Annotation Details for PDE4A


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Basic Information Top
Gene Symbol:PDE4A ( DPDE2,PDE4,PDE46 )
Gene Full Name: phosphodiesterase 4A, cAMP-specific
Band: 19p13.2
Quick LinksEntrez ID:5141; OMIM: 600126; Uniprot ID:PDE4A_HUMAN; ENSEMBL ID: ENSG00000065989; HGNC ID: 8780
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO:0016020TAS-membrane9677330
GO:0032587IEA-ruffle membrane-
GO:0048471IDA-perinuclear region of cytoplasm11306681
GO ID Evidence Qualifier GO_term References
GO:0004115IDA-3',5'-cyclic-AMP phosphodiesterase activity17404263
GO:0004115IGI-3',5'-cyclic-AMP phosphodiesterase activity8413254
GO:0004115TAS-3',5'-cyclic-AMP phosphodiesterase activity-
GO:0005515IPI-protein binding11306681
GO:0030552IGI-cAMP binding8413254
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006198IDA-cAMP catabolic process17404263
GO:0006198IEA-cAMP catabolic process-
GO:0006198IGI-cAMP catabolic process8413254
GO:0006198IMP-cAMP catabolic process17704206
GO:0007165IEA-signal transduction-
GO:0007608IEA-sensory perception of smell-
GO:0010738IEA-regulation of protein kinase A signaling-
GO:0035690IEA-cellular response to drug-
GO:0043949IEA-regulation of cAMP-mediated signaling-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PDE4ALYN11024510206997 Reconstituted Complex
PDE4ALYN11116710206997 Reconstituted Complex
PRKAR2APDE4A11116711296225 Affinity Capture-Western
PRKAR2APDE4A11156211296225 Affinity Capture-Western
AKAP6PDE4A11116711296225 Affinity Capture-Western
AKAP6PDE4A11485711296225 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99558
  • Data Attributes: MGI curated
No data