AutismKB 2.0

Annotation Details for PDE4B


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Basic Information Top
Gene Symbol:PDE4B ( DKFZp686F2182,DPDE4,MGC126529,PDE4B5,PDEIVB )
Gene Full Name: phosphodiesterase 4B, cAMP-specific
Band: 1p31.3
Quick LinksEntrez ID:5142; OMIM: 600127; Uniprot ID:PDE4B_HUMAN; ENSEMBL ID: ENSG00000184588; HGNC ID: 8781
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000930IEA-gamma-tubulin complex-
GO:0005813IEA-centrosome-
GO:0005829TAS-cytosol-
GO:0005891ISScolocalizes_withvoltage-gated calcium channel complex-
GO:0008021IEA-synaptic vesicle-
GO:0014069IEA-postsynaptic density-
GO:0030018ISS-Z disc-
GO:0043197IEA-dendritic spine-
GO:0060076IEA-excitatory synapse-
GO ID Evidence Qualifier GO_term References
GO:0004115IDA-3',5'-cyclic-AMP phosphodiesterase activity17404263
GO:0004115IGI-3',5'-cyclic-AMP phosphodiesterase activity8413254
GO:0004115ISS-3',5'-cyclic-AMP phosphodiesterase activity-
GO:0004115TAS-3',5'-cyclic-AMP phosphodiesterase activity-
GO:0030552IGI-cAMP binding8413254
GO:0043015IEA-gamma-tubulin binding-
GO:0044325ISS-ion channel binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001780ISS-neutrophil homeostasis-
GO:0006198IDA-cAMP catabolic process17404263
GO:0006198IEA-cAMP catabolic process-
GO:0006198IGI-cAMP catabolic process8413254
GO:0030593ISS-neutrophil chemotaxis-
GO:0032729IMP-positive regulation of interferon-gamma production17404263
GO:0032743IMP-positive regulation of interleukin-2 production17404263
GO:0035690ISS-cellular response to drug-
GO:0050852IMP-T cell receptor signaling pathway17404263
GO:0050900ISS-leukocyte migration-
GO:0071222ISS-cellular response to lipopolysaccharide-
GO:0071872ISS-cellular response to epinephrine stimulus-
GO:0086004ISS-regulation of cardiac muscle cell contraction-
GO:1901841ISS-regulation of high voltage-gated calcium channel activity-
GO:1901898ISS-negative regulation of relaxation of cardiac muscle-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
PDE4Brs10158178, rs10218482, rs1040716, rs10493389, rs11208756, rs11208758, rs11208769, rs11208776, rs11208794, rs11208796, rs11208816, rs12068439, rs12088813, rs12129539, rs12134699, rs12136401, rs12142070, rs12142375, rs12404118, rs12406476, rs12731764, rs12743648, rs12745871, rs1316871, rs1317611, rs1321177, rs1338719, rs1338721, rs1354060, rs1354061, rs1354064, rs1392812, rs1392816, rs1463884, rs1500958, rs1556805, rs1566527, rs1572680, rs1577844, rs1740417, rs17424885, rs17450973, rs1890196, rs1890197, rs1892346, rs1937450, rs1937456, rs1999856, rs2069278, rs2133967, rs2144719, rs2180335, rs2186123, rs2455032, rs2489907, rs2503161, rs2503166, rs2503174, rs2503177, rs2503185, rs2503220, rs2503222, rs2840677, rs3009872, rs3767311, rs4004, rs4077431, rs4259616, rs4288570, rs4313369, rs4320761, rs4329483, rs4353064, rs4384209, rs4454519, rs4503327, rs4557937, rs4592240, rs4655821, rs4655834, rs472952, rs483098, rs491190, rs498448, rs499320, rs502958, rs518476, rs522037, rs524770, rs526772, rs529601, rs531244, rs539322, rs544361, rs556303, rs566954, rs571146, rs583018, rs596662, rs598961, rs599235, rs599381, rs611838, rs614350, rs634460, rs6588169, rs6588174, rs6588186, rs6588190, rs6588193, rs6664618, rs6696880, rs6700403, rs6700971, rs7412571, rs7519259, rs7528545, rs7547294, rs782689, rs783036, rs783038, rs783039, rs783050, rs783061, rs783062, rs783066, rs910693, rs910694 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:99557
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-9570'