AutismKB 2.0

Annotation Details for ANAPC7


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Basic Information Top
Gene Symbol:ANAPC7 ( APC7 )
Gene Full Name: anaphase promoting complex subunit 7
Band: 12q24.11
Quick LinksEntrez ID:51434; OMIM: 606949; Uniprot ID:APC7_HUMAN; ENSEMBL ID: ENSG00000196510; HGNC ID: 17380
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus21241890
GO:0005654TAS-nucleoplasm-
GO:0005680IDA-anaphase-promoting complex16364912
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0019903IPI-protein phosphatase binding21241890
GO ID Evidence Qualifier GO_term References
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0042787TAS-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-
GO:0043161TAS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0051301IEA-cell division-
GO:0051436TAS-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0051439TAS-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0070979IDA-protein K11-linked ubiquitination18485873
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ANAPC7BUB1B11953810477750 Affinity Capture-Western
ANAPC7BUB1B10716610477750 Affinity Capture-Western
ANAPC7CDC2011953812956947 18997788 Affinity Capture-Western; Reconstituted Complex
ANAPC7CDC2010742712956947 18997788 Affinity Capture-Western; Reconstituted Complex
ANAPC7CDC2711953810922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
ANAPC7CDC2710743110922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
ANAPC7CDH111953812956947 Reconstituted Complex
ANAPC7CDH110743412956947 Reconstituted Complex
ANAPC7CREBBP11953816319895 Affinity Capture-Western; Reconstituted Complex
ANAPC7CREBBP10777716319895 Affinity Capture-Western; Reconstituted Complex
ANAPC7EP30010834716319895 Affinity Capture-Western
ANAPC7EP30011953816319895 Affinity Capture-Western
ANAPC7BAP111953819615732 Affinity Capture-MS
ANAPC7BAP111391119615732 Affinity Capture-MS
ANAPC7APC211953812956947 Affinity Capture-Western
ANAPC7ANAPC411898212956947 Affinity Capture-Western; Reconstituted Complex
ANAPC7ANAPC411953812956947 Affinity Capture-Western; Reconstituted Complex
ANAPC7FZR111948912956947 Reconstituted Complex
ANAPC7FZR111953812956947 Reconstituted Complex
ANAPC7ANAPC511953712956947 Reconstituted Complex
ANAPC7ANAPC511953812956947 Reconstituted Complex
ANAPC1ANAPC712222911076961 12956947 Co-purification; Reconstituted Complex
ANAPC1ANAPC711953811076961 12956947 Co-purification; Reconstituted Complex
CDT1ANAPC711953818162579 Affinity Capture-MS; Reconstituted Complex
CDT1ANAPC712355518162579 Affinity Capture-MS; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1929711
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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