AutismKB 2.0

Annotation Details for PDE8A


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Basic Information Top
Gene Symbol:PDE8A ( FLJ16150,HsT19550 )
Gene Full Name: phosphodiesterase 8A
Band: 15q25.3
Quick LinksEntrez ID:5151; OMIM: 602972; Uniprot ID:PDE8A_HUMAN; ENSEMBL ID: ENSG00000073417; HGNC ID: 8793
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0004114NAS-3',5'-cyclic-nucleotide phosphodiesterase activity9618252
GO:0004115TAS-3',5'-cyclic-AMP phosphodiesterase activity-
GO:0019900IPI-kinase binding23509299
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001934IMP-positive regulation of protein phosphorylation23509299
GO:0006198IEA-cAMP catabolic process-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0007165IEA-signal transduction-
GO:0009187NAS-cyclic nucleotide metabolic process9618252
GO:0060548IMP-negative regulation of cell death23509299
GO:0070374IMP-positive regulation of ERK1 and ERK2 cascade23509299
GO:0071364IMP-cellular response to epidermal growth factor stimulus23509299
GO:1903206IMP-negative regulation of hydrogen peroxide-induced cell death23509299
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1277116
  • Data Attributes: MGI curated and HomoloGene calculated
No data