AutismKB 2.0

Annotation Details for DTL


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Basic Information Top
Gene Symbol:DTL ( CDT2,DCAF2,L2DTL,RAMP )
Gene Full Name: denticleless homolog (Drosophila)
Band: 1q32.3
Quick LinksEntrez ID:51514; OMIM: 610617; Uniprot ID:DTL_HUMAN; ENSEMBL ID: ENSG00000143476; HGNC ID: 30288
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus17106265
GO:0005654TAS-nucleoplasm-
GO:0005694IEA-chromosome-
GO:0005730IDA-nucleolus-
GO:0005813IDA-centrosome17106265
GO:0005829IDA-cytosol-
GO:0031464IDA-Cul4A-RING E3 ubiquitin ligase complex17085480
GO:0031465IDA-Cul4B-RING E3 ubiquitin ligase complex18794347
GO:0031965IEA-nuclear membrane-
GO ID Evidence Qualifier GO_term References
GO:0004842IDAcontributes_toubiquitin-protein transferase activity18794347
GO:0005515IPI-protein binding17041588
GO ID Evidence Qualifier GO_term References
GO:0000209IDA-protein polyubiquitination18794347
GO:0000209TAS-protein polyubiquitination17085480
GO:0006260IEA-DNA replication-
GO:0006511IDA-ubiquitin-dependent protein catabolic process18794347
GO:0006511TAS-ubiquitin-dependent protein catabolic process17085480
GO:0006513IDA-protein monoubiquitination20129063
GO:0006974IDA-cellular response to DNA damage stimulus20129063
GO:0009411IDA-response to UV18794347
GO:0019985IDA-translesion synthesis20129063
GO:0031572IMP-G2 DNA damage checkpoint17085480
GO:0042769TAS-DNA damage response, detection of DNA damage-
GO:0043687TAS-post-translational protein modification-
GO:0051726IMP-regulation of cell cycle17085480
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DTLCDKN1A10746018703516 18794347 Affinity Capture-Western; Biochemical Activity
DTLCDKN1A11958218703516 18794347 Affinity Capture-Western; Biochemical Activity
DTLDDB110800916949367 17041588 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
DTLDDB111958216949367 17041588 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
DTLCUL4B11958216949367 17041588 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
DTLCUL4B11402816949367 17041588 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
DTLCUL4A11958216949367 17041588 Affinity Capture-Western; Reconstituted Complex
DTLCUL4A11402916949367 17041588 Affinity Capture-Western; Reconstituted Complex
DTLCOPS611958219615732 Affinity Capture-MS
DTLCOPS611617619615732 Affinity Capture-MS
DTLWDR511958217041588 Affinity Capture-Western
DTLWDR511627217041588 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1924093
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020419-34'