AutismKB 2.0

Annotation Details for PDE9A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PDE9A ( FLJ90181,HSPDE9A2 )
Gene Full Name: phosphodiesterase 9A
Band: 21q22.3
Quick LinksEntrez ID:5152; OMIM: 602973; Uniprot ID:PDE9A_HUMAN; ENSEMBL ID: ENSG00000160191; HGNC ID: 8795
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005783IEA-endoplasmic reticulum-
GO:0005794IEA-Golgi apparatus-
GO:0005829IDA-cytosol16780588
GO:0005829TAS-cytosol-
GO:0032587IEA-ruffle membrane-
GO:0042383IDA-sarcolemma25799991
GO:0043204IEA-perikaryon-
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0004114TAS-3',5'-cyclic-nucleotide phosphodiesterase activity9856478
GO:0005515IPI-protein binding16189514
GO:0046872IEA-metal ion binding-
GO:0047555IDA-3',5'-cyclic-GMP phosphodiesterase activity9624146
GO:0047555TAS-3',5'-cyclic-GMP phosphodiesterase activity-
GO ID Evidence Qualifier GO_term References
GO:0007165TAS-signal transduction9856478
GO:0010613ISS-positive regulation of cardiac muscle hypertrophy-
GO:0019934IEA-cGMP-mediated signaling-
GO:0046068IDA-cGMP metabolic process9624146
GO:0046069IDA-cGMP catabolic process25799991
GO:0046069IEA-cGMP catabolic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TRIM32PDE9A11117816189514 Two-hybrid
TRIM32PDE9A11660816189514 Two-hybrid
PDE9APDE9A11117816189514 Two-hybrid
PHYHIPLPDE9A12409216189514 Two-hybrid
PHYHIPLPDE9A11117816189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018