Annotation Details for PIAS4


Gene Symbol: | PIAS4 ( FLJ12419,MGC35296,PIASY,Piasg,ZMIZ6 ) |
---|---|
Gene Full Name: | protein inhibitor of activated STAT, 4 |
Band: | 19p13.3 |
Quick Links | Entrez ID:51588; OMIM: 605989; Uniprot ID:PIAS4_HUMAN; ENSEMBL ID: ENSG00000105229; HGNC ID: 17002 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005634 | IDA | - | nucleus | 11248056 |
GO:0005634 | NAS | - | nucleus | 9724754 |
GO:0005654 | TAS | - | nucleoplasm | - |
GO:0005737 | IDA | - | cytoplasm | 16816390 |
GO:0016363 | IEA | - | nuclear matrix | - |
GO:0016605 | IEA | - | PML body | - |
GO:1990234 | IEA | - | transferase complex | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0003677 | IEA | - | DNA binding | - |
GO:0003714 | IEA | - | transcription corepressor activity | - |
GO:0005515 | IPI | - | protein binding | 11388671 |
GO:0008022 | IEA | - | protein C-terminus binding | - |
GO:0008270 | NAS | - | zinc ion binding | 9724754 |
GO:0019789 | EXP | - | SUMO transferase activity | 11731474 |
GO:0019789 | IMP | - | SUMO transferase activity | 22508508 |
GO:0019789 | TAS | - | SUMO transferase activity | - |
GO:0031625 | IPI | - | ubiquitin protein ligase binding | 16816390 |
GO:0061665 | IDA | - | SUMO ligase activity | 18579533 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000122 | IEA | - | negative regulation of transcription from RNA polymerase II promoter | - |
GO:0006303 | TAS | - | double-strand break repair via nonhomologous end joining | - |
GO:0006351 | IEA | - | transcription, DNA-templated | - |
GO:0010804 | IEA | - | negative regulation of tumor necrosis factor-mediated signaling pathway | - |
GO:0016055 | IEA | - | Wnt signaling pathway | - |
GO:0016925 | IDA | - | protein sumoylation | 18579533 |
GO:0016925 | IEA | - | protein sumoylation | - |
GO:0016925 | IMP | - | protein sumoylation | 22508508 |
GO:0016925 | TAS | - | protein sumoylation | - |
GO:0032088 | IEA | - | negative regulation of NF-kappaB transcription factor activity | - |
GO:0033235 | IDA | - | positive regulation of protein sumoylation | 17696781 |
GO:0045892 | IDA | - | negative regulation of transcription, DNA-templated | 11248056 |
GO:0045892 | NAS | - | negative regulation of transcription, DNA-templated | 9724754 |
GO:1902174 | ISS | - | positive regulation of keratinocyte apoptotic process | - |
GO:1902231 | IEA | - | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage | - |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
PIAS4 | PARP1 | 106652 | 19779455 | Affinity Capture-Western; Reconstituted Complex |
PIAS4 | PARP1 | 119624 | 19779455 | Affinity Capture-Western; Reconstituted Complex |
PIAS4 | AR | 106862 | 11439351 14981544 | Reconstituted Complex |
PIAS4 | AR | 119624 | 11439351 14981544 | Reconstituted Complex |
PIAS4 | BRCA1 | 107140 | 20016594 20016603 | Biochemical Activity; Co-localization |
PIAS4 | BRCA1 | 119624 | 20016594 20016603 | Biochemical Activity; Co-localization |
PIAS4 | CEBPD | 107481 | 18477566 | Reconstituted Complex |
PIAS4 | CEBPD | 119624 | 18477566 | Reconstituted Complex |
PIAS4 | ETS1 | 119624 | 17456046 | Affinity Capture-Western |
PIAS4 | ETS1 | 108414 | 17456046 | Affinity Capture-Western |
PIAS4 | HDAC1 | 119624 | 14981544 | Reconstituted Complex |
PIAS4 | HDAC1 | 109315 | 14981544 | Reconstituted Complex |
PIAS4 | HDAC2 | 119624 | 14981544 | Reconstituted Complex |
PIAS4 | HDAC2 | 109316 | 14981544 | Reconstituted Complex |
PIAS4 | SMAD1 | 110261 | 12904571 | Affinity Capture-Western; Two-hybrid |
PIAS4 | SMAD1 | 119624 | 12904571 | Affinity Capture-Western; Two-hybrid |
PIAS4 | SMAD2 | 110262 | 12815042 12904571 | Affinity Capture-Western; Two-hybrid |
PIAS4 | SMAD2 | 119624 | 12815042 12904571 | Affinity Capture-Western; Two-hybrid |
PIAS4 | SMAD3 | 110263 | 12815042 12904571 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
PIAS4 | SMAD3 | 119624 | 12815042 12904571 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
PIAS4 | SMAD4 | 110264 | 12740389 12815042 12904571 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
PIAS4 | SMAD4 | 119624 | 12740389 12815042 12904571 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
PIAS4 | SMAD6 | 110266 | 12815042 | Affinity Capture-Western; Two-hybrid |
PIAS4 | SMAD6 | 119624 | 12815042 | Affinity Capture-Western; Two-hybrid |
PIAS4 | SMAD7 | 119624 | 12815042 | Affinity Capture-Western; Two-hybrid |
PIAS4 | SMAD7 | 110267 | 12815042 | Affinity Capture-Western; Two-hybrid |
PIAS4 | TRIM27 | 111919 | 15907835 | Affinity Capture-Western; Two-hybrid |
PIAS4 | TRIM27 | 119624 | 15907835 | Affinity Capture-Western; Two-hybrid |
PIAS4 | SUMO3 | 112496 | 20016603 | Co-localization |
PIAS4 | SUMO3 | 119624 | 20016603 | Co-localization |
PIAS4 | SUMO2 | 112497 | 19394292 20016603 | Affinity Capture-MS; Co-localization |
PIAS4 | SUMO2 | 119624 | 19394292 20016603 | Affinity Capture-MS; Co-localization |
PIAS4 | TCF4 | 112787 | 20211142 | Two-hybrid |
PIAS4 | TCF4 | 119624 | 20211142 | Two-hybrid |
PIAS4 | TP53BP1 | 113011 | 20016603 | Co-localization |
PIAS4 | TP53BP1 | 119624 | 20016603 | Co-localization |
PIAS4 | SUMO1 | 113188 | 20016603 | Co-localization |
PIAS4 | SUMO1 | 119624 | 20016603 | Co-localization |
PIAS4 | CALCOCO2 | 115535 | 16189514 | Two-hybrid |
PIAS4 | CALCOCO2 | 119624 | 16189514 | Two-hybrid |
PIAS4 | LEF1 | 119354 | 11731474 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
PIAS4 | LEF1 | 119624 | 11731474 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
ZMIZ2 | PIAS4 | 119624 | 20159969 | Affinity Capture-Western |
ZMIZ2 | PIAS4 | 123701 | 20159969 | Affinity Capture-Western |
No data |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
PIAS4 | CALCOCO2 | 06846 | 16189514 | - |
PIAS4 | CALCOCO2 | 06910 | 16189514 | - |
- MGI ID: MGI:2136940
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-040426-1298