AutismKB 2.0

Annotation Details for PDHA1


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Basic Information Top
Gene Symbol:PDHA1 ( PDHA,PDHCE1A,PHE1A )
Gene Full Name: pyruvate dehydrogenase (lipoamide) alpha 1
Band: Xp22.12
Quick LinksEntrez ID:5160; OMIM: 300502; Uniprot ID:ODPA_HUMAN; ENSEMBL ID: ENSG00000131828; HGNC ID: 8806
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus21630459
GO:0005730IDA-nucleolus-
GO:0005739IDA-mitochondrion20833797
GO:0005759TAS-mitochondrial matrix-
GO:0043209IEA-myelin sheath-
GO:0045254IDA-pyruvate dehydrogenase complex19081061
GO ID Evidence Qualifier GO_term References
GO:0004738IDA-pyruvate dehydrogenase activity19081061
GO:0004739IEA-pyruvate dehydrogenase (acetyl-transferring) activity-
GO:0034604IEA-pyruvate dehydrogenase (NAD+) activity-
GO ID Evidence Qualifier GO_term References
GO:0006006IEA-glucose metabolic process-
GO:0006086IDA-acetyl-CoA biosynthetic process from pyruvate19081061
GO:0006090TAS-pyruvate metabolic process-
GO:0006099IDA-tricarboxylic acid cycle19081061
GO:0010510TAS-regulation of acetyl-CoA biosynthetic process from pyruvate-
GO:0034641TAS-cellular nitrogen compound metabolic process-
GO:0061732IEA-mitochondrial acetyl-CoA biosynthetic process from pyruvate-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PDHA1EIF611118616169070 Two-hybrid
PDHA1EIF610989816169070 Two-hybrid
PDHBPDHA11111867864652 Co-purification
PDHBPDHA11111887864652 Co-purification
DGKEPDHA111118617353931 Affinity Capture-MS
DGKEPDHA111409617353931 Affinity Capture-MS
USP19PDHA111118619615732 Affinity Capture-MS
USP19PDHA111607819615732 Affinity Capture-MS
C19orf62PDHA111118619615732 Affinity Capture-MS
C19orf62PDHA111885519615732 Affinity Capture-MS
WDR20PDHA111118619615732 Affinity Capture-MS
WDR20PDHA112488419615732 Affinity Capture-MS
C12orf44PDHA111118620562859 Affinity Capture-MS
C12orf44PDHA112194820562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97532
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2719'