Annotation Details for PDK1


Gene Symbol: | PDK1 ( - ) |
---|---|
Gene Full Name: | pyruvate dehydrogenase kinase, isozyme 1 |
Band: | 2q31.1 |
Quick Links | Entrez ID:5163; OMIM: 602524; Uniprot ID:PDK1_HUMAN; ENSEMBL ID: ENSG00000152256; HGNC ID: 8809 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005634 | IDA | - | nucleus | - |
GO:0005730 | IDA | - | nucleolus | - |
GO:0005739 | IDA | - | mitochondrion | - |
GO:0005759 | TAS | - | mitochondrial matrix | - |
GO:0005967 | IEA | - | mitochondrial pyruvate dehydrogenase complex | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0004672 | IDA | - | protein kinase activity | 17683942 |
GO:0004740 | EXP | - | pyruvate dehydrogenase (acetyl-transferring) kinase activity | 11485553 |
GO:0004740 | IDA | - | pyruvate dehydrogenase (acetyl-transferring) kinase activity | 7499431 |
GO:0004740 | IMP | - | pyruvate dehydrogenase (acetyl-transferring) kinase activity | 22195962 |
GO:0005515 | IPI | - | protein binding | 17110931 |
GO:0005524 | IEA | - | ATP binding | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0006006 | IEA | - | glucose metabolic process | - |
GO:0006468 | IEA | - | protein phosphorylation | - |
GO:0008283 | IMP | - | cell proliferation | 18541534 |
GO:0008631 | IMP | - | intrinsic apoptotic signaling pathway in response to oxidative stress | 18541534 |
GO:0010510 | TAS | - | regulation of acetyl-CoA biosynthetic process from pyruvate | - |
GO:0010906 | IMP | - | regulation of glucose metabolic process | 18541534 |
GO:0097411 | IMP | - | hypoxia-inducible factor-1alpha signaling pathway | 21763680 |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
PDK1 | DLAT | 111189 | 11978179 | Reconstituted Complex |
PDK1 | DLAT | 108081 | 11978179 | Reconstituted Complex |
PDK1 | MTOR | 111189 | 10567431 | Phenotypic Enhancement |
PDK1 | MTOR | 108757 | 10567431 | Phenotypic Enhancement |
PKN1 | PDK1 | 111189 | 10753910 | Affinity Capture-Western |
PKN1 | PDK1 | 111571 | 10753910 | Affinity Capture-Western |
PKN2 | PDK1 | 111189 | 10753910 | Affinity Capture-Western |
PKN2 | PDK1 | 111572 | 10753910 | Affinity Capture-Western |
RPS6KB1 | PDK1 | 111189 | 11733037 | Reconstituted Complex |
RPS6KB1 | PDK1 | 112112 | 11733037 | Reconstituted Complex |
RALGDS | PDK1 | 111189 | 11889038 | Affinity Capture-Western |
RALGDS | PDK1 | 111836 | 11889038 | Affinity Capture-Western |
RPTOR | PDK1 | 111189 | 12150926 | Affinity Capture-Western |
RPTOR | PDK1 | 121582 | 12150926 | Affinity Capture-Western |
PDK2 | PDK1 | 111189 | 12573248 | Reconstituted Complex |
PDK2 | PDK1 | 111190 | 12573248 | Reconstituted Complex |
No data |
No data |