AutismKB 2.0

Annotation Details for ENPP2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ENPP2 ( ATX,ATX-X,AUTOTAXIN,FLJ26803,LysoPLD,NPP2,PD-IALPHA,PDNP2 )
Gene Full Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
Band: 8q24.12
Quick LinksEntrez ID:5168; OMIM: 601060; Uniprot ID:ENPP2_HUMAN; ENSEMBL ID: ENSG00000136960; HGNC ID: 3357
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IDA-extracellular space15280042
GO:0005615ISS-extracellular space-
GO:0005886TAS-plasma membrane8579579
GO:0005887TAS-integral component of plasma membrane1733949
GO ID Evidence Qualifier GO_term References
GO:0003676IEA-nucleic acid binding-
GO:0004528IEA-phosphodiesterase I activity-
GO:0004551IEA-nucleotide diphosphatase activity-
GO:0004622IDA-lysophospholipase activity15280042
GO:0005044IEA-scavenger receptor activity-
GO:0005509ISS-calcium ion binding-
GO:0008134TAS-transcription factor binding8586446
GO:0008270ISS-zinc ion binding-
GO:0016787TAS-hydrolase activity7982964
GO:0030247IEA-polysaccharide binding-
GO:0047391IEA-alkylglycerophosphoethanolamine phosphodiesterase activity-
GO ID Evidence Qualifier GO_term References
GO:0006796TAS-phosphate-containing compound metabolic process8579579
GO:0006898IEA-receptor-mediated endocytosis-
GO:0006935NAS-chemotaxis7982964
GO:0006955IEA-immune response-
GO:0007186TAS-G-protein coupled receptor signaling pathway1733949
GO:0009395IDA-phospholipid catabolic process15280042
GO:0010634IGI-positive regulation of epithelial cell migration18054784
GO:0010634IMP-positive regulation of epithelial cell migration18054784
GO:0030334IDA-regulation of cell migration1733949
GO:0034638IDA-phosphatidylcholine catabolic process21240271
GO:0045765IEA-regulation of angiogenesis-
GO:0048870TAS-cell motility1733949
GO:0050731IDA-positive regulation of peptidyl-tyrosine phosphorylation18054784
GO:0090305IEA-nucleic acid phosphodiester bond hydrolysis-
GO:2000394IGI-positive regulation of lamellipodium morphogenesis18054784
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
ENPP2rs2305125, rs935359 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:1321390
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1156'