Annotation Details for NLK


Gene Symbol: | NLK ( DKFZp761G1211,FLJ21033 ) |
---|---|
Gene Full Name: | nemo-like kinase |
Band: | 17q11.2 |
Quick Links | Entrez ID:51701; OMIM: 609476; Uniprot ID:NLK_HUMAN; ENSEMBL ID: ENSG00000087095; HGNC ID: 29858 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005634 | IBA | - | nucleus | - |
GO:0005634 | ISS | - | nucleus | - |
GO:0005654 | TAS | - | nucleoplasm | - |
GO:0005737 | IBA | - | cytoplasm | - |
GO:0005829 | TAS | - | cytosol | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000287 | ISS | - | magnesium ion binding | - |
GO:0004672 | TAS | - | protein kinase activity | 10863097 |
GO:0004674 | TAS | - | protein serine/threonine kinase activity | - |
GO:0004707 | IBA | - | MAP kinase activity | - |
GO:0004707 | ISS | - | MAP kinase activity | - |
GO:0005515 | IPI | - | protein binding | 15764709 |
GO:0005524 | ISS | - | ATP binding | - |
GO:0008134 | IPI | - | transcription factor binding | 16714285 |
GO:0031625 | IPI | - | ubiquitin protein ligase binding | 16714285 |
GO:0042169 | ISS | - | SH2 domain binding | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000165 | IEA | - | MAPK cascade | - |
GO:0006351 | IEA | - | transcription, DNA-templated | - |
GO:0006355 | ISS | - | regulation of transcription, DNA-templated | - |
GO:0006468 | ISS | - | protein phosphorylation | - |
GO:0007179 | IMP | - | transforming growth factor beta receptor signaling pathway | 15004007 |
GO:0007223 | TAS | - | Wnt signaling pathway, calcium modulating pathway | - |
GO:0010468 | IBA | - | regulation of gene expression | - |
GO:0018107 | ISS | - | peptidyl-threonine phosphorylation | - |
GO:0030178 | ISS | - | negative regulation of Wnt signaling pathway | - |
GO:0035556 | IBA | - | intracellular signal transduction | - |
GO:0035556 | ISS | - | intracellular signal transduction | - |
GO:0042501 | ISS | - | serine phosphorylation of STAT protein | - |
GO:0046777 | IEA | - | protein autophosphorylation | - |
GO:0050821 | IDA | - | protein stabilization | 25512613 |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
NLK | CREBBP | 119685 | 16055500 | Affinity Capture-Western |
NLK | CREBBP | 107777 | 16055500 | Affinity Capture-Western |
NLK | CTNNB1 | 119685 | 12556497 | Affinity Capture-Western |
NLK | CTNNB1 | 107880 | 12556497 | Affinity Capture-Western |
NLK | MYB | 119685 | 15082531 16055500 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex |
NLK | MYB | 110687 | 15082531 16055500 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex |
NLK | MYBL1 | 119685 | 16055500 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex |
NLK | MYBL1 | 110688 | 16055500 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex |
NLK | MYBL2 | 110690 | 16055500 | Affinity Capture-Western |
NLK | MYBL2 | 119685 | 16055500 | Affinity Capture-Western |
NLK | PPARG | 119685 | 17952062 | Affinity Capture-Western; Co-purification; Reconstituted Complex |
NLK | PPARG | 111464 | 17952062 | Affinity Capture-Western; Co-purification; Reconstituted Complex |
NLK | FBXW4 | 119685 | 18765672 | Affinity Capture-Western |
NLK | FBXW4 | 112364 | 18765672 | Affinity Capture-Western |
NLK | SKP2 | 119685 | 18765672 | Affinity Capture-Western |
NLK | SKP2 | 112393 | 18765672 | Affinity Capture-Western |
NLK | TCF7L2 | 119685 | 12556497 | Affinity Capture-Western |
NLK | TCF7L2 | 112795 | 12556497 | Affinity Capture-Western |
NLK | UBC | 119685 | 17894482 | Affinity Capture-Western |
NLK | UBC | 113164 | 17894482 | Affinity Capture-Western |
NLK | CUL1 | 114032 | 18765672 | Affinity Capture-Western |
NLK | CUL1 | 119685 | 18765672 | Affinity Capture-Western |
NLK | SETDB1 | 115202 | 17952062 | Affinity Capture-Western; Co-purification |
NLK | SETDB1 | 119685 | 17952062 | Affinity Capture-Western; Co-purification |
NLK | HIPK2 | 119685 | 15082531 | Reconstituted Complex; Two-hybrid |
NLK | HIPK2 | 118815 | 15082531 | Reconstituted Complex; Two-hybrid |
NLK | LEF1 | 119685 | 12556497 | Affinity Capture-Western |
NLK | LEF1 | 119354 | 12556497 | Affinity Capture-Western |
CHD7 | NLK | 119685 | 17952062 | Affinity Capture-Western; Co-purification; Reconstituted Complex |
CHD7 | NLK | 120775 | 17952062 | Affinity Capture-Western; Co-purification; Reconstituted Complex |
FBXW5 | NLK | 119685 | 18765672 | Affinity Capture-Western |
FBXW5 | NLK | 119967 | 18765672 | Affinity Capture-Western |
No data |
No data |
- MGI ID: MGI:1201387
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-040701-1