AutismKB 2.0

Annotation Details for SERPINF1


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Basic Information Top
Gene Symbol:SERPINF1 ( EPC-1,PEDF )
Gene Full Name: serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Band: 17p13.3
Quick LinksEntrez ID:5176; OMIM: 172860; Uniprot ID:PEDF_HUMAN; ENSEMBL ID: ENSG00000132386; HGNC ID: 8824
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IDA-extracellular region12737624
GO:0005604IEA-basement membrane-
GO:0005615IDA-extracellular space20551380
GO:0031012IDAcolocalizes_withextracellular matrix20551380
GO:0042470IEA-melanosome-
GO:0043203IEA-axon hillock-
GO:0048471IEA-perinuclear region of cytoplasm-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0004867TAS-serine-type endopeptidase inhibitor activity8473338
GO:0005515IPI-protein binding25416956
GO ID Evidence Qualifier GO_term References
GO:0001822IEA-kidney development-
GO:0007275TAS-multicellular organism development8473338
GO:0007568IEA-aging-
GO:0007614IEA-short-term memory-
GO:0008283TAS-cell proliferation8473338
GO:0010447IEA-response to acidic pH-
GO:0010596IEA-negative regulation of endothelial cell migration-
GO:0010629IEA-negative regulation of gene expression-
GO:0010951IEA-negative regulation of endopeptidase activity-
GO:0010976IEA-positive regulation of neuron projection development-
GO:0016525IDA-negative regulation of angiogenesis11562499
GO:0042698IEA-ovulation cycle-
GO:0046685IEA-response to arsenic-containing substance-
GO:0050728IEA-negative regulation of inflammatory response-
GO:0050769IDA-positive regulation of neurogenesis8226833
GO:0060041IEA-retina development in camera-type eye-
GO:0060770IEA-negative regulation of epithelial cell proliferation involved in prostate gland development-
GO:0071279IEA-cellular response to cobalt ion-
GO:0071300IEA-cellular response to retinoic acid-
GO:0071333IEA-cellular response to glucose stimulus-
GO:0071549IEA-cellular response to dexamethasone stimulus-
GO:1901215IEA-negative regulation of neuron death-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:108080
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040912-2'