AutismKB 2.0

Annotation Details for ZAK


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Basic Information Top
Gene Symbol:ZAK ( AZK,MLK7,MLT,MLTK,MRK,mlklak,pk )
Gene Full Name: -
Band: 2q24.2
Quick LinksEntrez ID:51776; OMIM: 609479; Uniprot ID:MLTK_HUMAN; ENSEMBL ID: ENSG00000091436; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005737IBA-cytoplasm-
GO:0005737ISS-cytoplasm-
GO:0005829IDA-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0000287IDA-magnesium ion binding11836244
GO:0003723IDA-RNA binding22681889
GO:0004674IDA-protein serine/threonine kinase activity11836244
GO:0004709IDA-MAP kinase kinase kinase activity11836244
GO:0005515IPI-protein binding21988832
GO:0005524IDA-ATP binding11836244
GO ID Evidence Qualifier GO_term References
GO:0000075IDA-cell cycle checkpoint15342622
GO:0000077IMP-DNA damage checkpoint11836244
GO:0000186TAS-activation of MAPKK activity11836244
GO:0006468IDA-protein phosphorylation11836244
GO:0006950NAS-response to stress11836244
GO:0007010IEA-cytoskeleton organization-
GO:0007050IMP-cell cycle arrest11836244
GO:0007257IDA-activation of JUN kinase activity11836244
GO:0008219NAS-cell death11836244
GO:0008283NAS-cell proliferation11836244
GO:0009314IDA-response to radiation11836244
GO:0030154NAS-cell differentiation11836244
GO:0035556IDA-intracellular signal transduction11836244
GO:0042733IMP-embryonic digit morphogenesis26755636
GO:0043065IDA-positive regulation of apoptotic process10924358
GO:0060173IMP-limb development26755636
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ZAKSFN10907215778465 Affinity Capture-MS
ZAKSFN11972515778465 Affinity Capture-MS
ZAKMAP2K711972515465036 Affinity Capture-Western
ZAKMAP2K711159515465036 Affinity Capture-Western
ZAKTGFBR111972515465036 Affinity Capture-Western
ZAKTGFBR111290415465036 Affinity Capture-Western
ZAKZNF33A11972512535642 Affinity Capture-Western; Two-hybrid
ZAKZNF33A11341012535642 Affinity Capture-Western; Two-hybrid
ZAKZAK11972510924358 15485649 Affinity Capture-Western
ZNF567ZAK11972516189514 Two-hybrid
ZNF567ZAK12784816189514 Two-hybrid
No data
Gene Symbol Interactant Interaction ID References Description
ZAKZAK1179110924358 15485649|17192257 -
ZNF567ZAK1172816189514 -
ZNF567ZAK1179116189514 -
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2443258
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050417-29'