AutismKB 2.0

Annotation Details for PFDN5


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Basic Information Top
Gene Symbol:PFDN5 ( MGC5329,MGC71907,MM-1,MM1,PFD5 )
Gene Full Name: prefoldin subunit 5
Band: 12q13.13
Quick LinksEntrez ID:5204; OMIM: 604899; Uniprot ID:PFD5_HUMAN; ENSEMBL ID: ENSG00000123349; HGNC ID: 8869
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005737TAS-cytoplasm16130169
GO:0016272IBA-prefoldin complex-
GO ID Evidence Qualifier GO_term References
GO:0003714TAS-transcription corepressor activity9792694
GO:0005515IPI-protein binding17728244
GO:0051082IEA-unfolded protein binding-
GO ID Evidence Qualifier GO_term References
GO:0006355TAS-regulation of transcription, DNA-templated9792694
GO:0006457IEA-protein folding-
GO:0045892IMP-negative regulation of transcription, DNA-templated18281035
GO:0060041IEA-retina development in camera-type eye-
GO:0090090IMP-negative regulation of canonical Wnt signaling pathway18281035
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PFDN5EGR111122618281035 Affinity Capture-Western
PFDN5EGR110827818281035 Affinity Capture-Western
PFDN5HDAC110931511585818 Affinity Capture-Western
PFDN5HDAC111122611585818 Affinity Capture-Western
PFDN5MYC1106949792694 11567024 11585818 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PFDN5MYC1112269792694 11567024 11585818 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SIN3APFDN511122611585818 Affinity Capture-Western
SIN3APFDN511743911585818 Affinity Capture-Western
TRIM28PFDN511545711585818 Affinity Capture-Western; Two-hybrid
TRIM28PFDN511122611585818 Affinity Capture-Western; Two-hybrid
PFDN6PFDN511122614634002 Co-purification
PFDN6PFDN511573414634002 Co-purification
SP1PFDN511122618281035 Affinity Capture-Western
SP1PFDN511255018281035 Affinity Capture-Western
PRPF4PFDN511122619615732 Affinity Capture-MS
PRPF4PFDN511457619615732 Affinity Capture-MS
IKBKGPFDN511408920098747 Reconstituted Complex
IKBKGPFDN511122620098747 Reconstituted Complex
Gene Symbol Interactant Interaction ID References Description
TP73PFDN518264811844794 MM1 interacts with p73-alpha.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1928753
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6858'