Annotation Details for PFKFB2
Basic Information Top
| Gene Symbol: | PFKFB2 ( DKFZp781D2217,MGC138308,MGC138310,PFK-2/FBPase-2 ) |
|---|---|
| Gene Full Name: | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| Band: | 1q32.1 |
| Quick Links | Entrez ID:5208; OMIM: 171835; Uniprot ID:F262_HUMAN; ENSEMBL ID: ENSG00000123836; HGNC ID: 8873 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005829 | TAS | - | cytosol | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0003873 | EXP | - | 6-phosphofructo-2-kinase activity | 2837207 |
| GO:0003873 | IDA | - | 6-phosphofructo-2-kinase activity | 11069105 |
| GO:0004331 | IEA | - | fructose-2,6-bisphosphate 2-phosphatase activity | - |
| GO:0005515 | IPI | - | protein binding | 8387495 |
| GO:0005524 | IEA | - | ATP binding | - |
| GO:0019901 | IPI | - | protein kinase binding | 11069105 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0006000 | IEA | - | fructose metabolic process | - |
| GO:0006003 | IEA | - | fructose 2,6-bisphosphate metabolic process | - |
| GO:0006089 | IEA | - | lactate metabolic process | - |
| GO:0006096 | IDA | - | glycolytic process | 11069105 |
| GO:0009749 | IEA | - | response to glucose | - |
| GO:0016311 | IEA | - | dephosphorylation | - |
| GO:0032024 | IEA | - | positive regulation of insulin secretion | - |
| GO:0033133 | IEA | - | positive regulation of glucokinase activity | - |
| GO:0046835 | IEA | - | carbohydrate phosphorylation | - |
| GO:0061621 | TAS | - | canonical glycolysis | - |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| PFKFB2 | GCK | 108915 | 11522786 | Two-hybrid |
| PFKFB2 | GCK | 111229 | 11522786 | Two-hybrid |
| YWHAQ | PFKFB2 | 116168 | 12853467 | Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex |
| YWHAQ | PFKFB2 | 111229 | 12853467 | Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex |
| No data |
| No data |
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