AutismKB 2.0

Annotation Details for CDK14


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Basic Information Top
Gene Symbol:CDK14 ( KIAA0834,PFTAIRE1,PFTK1 )
Gene Full Name: cyclin-dependent kinase 14
Band: 7q21.13
Quick LinksEntrez ID:5218; OMIM: 610679; Uniprot ID:CDK14_HUMAN; ENSEMBL ID: ENSG00000058091; HGNC ID: 8883
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000308IDA-cytoplasmic cyclin-dependent protein kinase holoenzyme complex19524571
GO:0005634IBA-nucleus-
GO:0005634IDA-nucleus-
GO:0005737TAS-cytoplasm9202329
GO:0005829IBA-cytosol-
GO:0005829IDA-cytosol-
GO:0005886IDA-plasma membrane19524571
GO ID Evidence Qualifier GO_term References
GO:0004693IMP-cyclin-dependent protein serine/threonine kinase activity19524571
GO:0005515IPI-protein binding16775625
GO:0005524IEA-ATP binding-
GO:0030332IPI-cyclin binding19524571
GO ID Evidence Qualifier GO_term References
GO:0000086IDA-G2/M transition of mitotic cell cycle20059949
GO:0006468IEA-protein phosphorylation-
GO:0016055IEA-Wnt signaling pathway-
GO:0051301IEA-cell division-
GO:0051726IEA-regulation of cell cycle-
GO:0060828IDA-regulation of canonical Wnt signaling pathway20059949
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CDK14IGHA211123917353931 Affinity Capture-MS
CDK14IGHA210971517353931 Affinity Capture-MS
SEPT8CDK1411123912098780 Affinity Capture-Western; Two-hybrid
SEPT8CDK1411678812098780 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:894318
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018