AutismKB 2.0

Annotation Details for ABCB1


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Basic Information Top
Gene Symbol:ABCB1 ( ABC20,CD243,CLCS,GP170,MDR1,MGC163296,P-GP,PGY1 )
Gene Full Name: ATP-binding cassette, sub-family B (MDR/TAP), member 1
Band: 7q21.12
Quick LinksEntrez ID:5243; OMIM: 171050; Uniprot ID:MDR1_HUMAN; ENSEMBL ID: ENSG00000085563; HGNC ID: 40
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0009986IDA-cell surface19384922
GO:0016020TAS-membrane3022150
GO:0016021IEA-integral component of membrane-
GO:0016324IDA-apical plasma membrane8898203
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005215TAS-transporter activity3022150
GO:0005515IPI-protein binding17088979
GO:0005524IEA-ATP binding-
GO:0008559TAS-xenobiotic-transporting ATPase activity-
GO:0042626TAS-ATPase activity, coupled to transmembrane movement of substances3022150
GO:0090554IDA-phosphatidylcholine-translocating ATPase activity8898203
GO:0090555IDA-phosphatidylethanolamine-translocating ATPase activity8898203
GO:0099038IDA-ceramide-translocating ATPase activity8898203
GO ID Evidence Qualifier GO_term References
GO:0000086IDA-G2/M transition of mitotic cell cycle19384922
GO:0006810TAS-transport3022150
GO:0006855IEA-drug transmembrane transport-
GO:0042493TAS-response to drug3022150
GO:0042908IEA-xenobiotic transport-
GO:0045332IDA-phospholipid translocation8898203
GO:0047484IMP-regulation of response to osmotic stress7828597
GO:0055085TAS-transmembrane transport-
GO:0072089IMP-stem cell proliferation19384922
GO:0099040IDA-ceramide translocation8898203
GO:1901529IMP-positive regulation of anion channel activity7828597
GO:2001225IMP-regulation of chloride transport7828597
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ABCB1DHX911126214769796 Affinity Capture-MS
ABCB1DHX910802514769796 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
ABCB1rs1045642, rs1128503, rs2032582 Gene overview in AlzGene
Gene Symbol Poly Names Gene overview in PDGene
ABCB1rs1045642, rs1128503, rs1202169, rs2032582, rs2229109, rs2235035, rs2235048, rs3213619, rs34976462, rs3842, rs55852620 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
ABCB1ABCB1_-1517T/C, rs1045642, rs1202169, rs2032582, rs3213619 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:97570
  • Data Attributes: MGI curated and HomoloGene calculated
No data