AutismKB 2.0

Annotation Details for PIK3C2A


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Basic Information Top
Gene Symbol:PIK3C2A ( CPK,DKFZp686L193,MGC142218,PI3-K-C2(ALPHA),PI3-K-C2A )
Gene Full Name: phosphoinositide-3-kinase, class 2, alpha polypeptide
Band: 11p15.1
Quick LinksEntrez ID:5286; OMIM: 603601; Uniprot ID:P3C2A_HUMAN; ENSEMBL ID: ENSG00000011405; HGNC ID: 8971
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus-
GO:0005737IDA-cytoplasm21081650
GO:0005794IEA-Golgi apparatus-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane21081650
GO:0005942IBA-phosphatidylinositol 3-kinase complex-
GO:0016020IDA-membrane19946888
GO:0030136IEA-clathrin-coated vesicle-
GO:0031982IDA-vesicle21081650
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005524IEA-ATP binding-
GO:0016303TAS-1-phosphatidylinositol-3-kinase activity9337861
GO:0035004TAS-phosphatidylinositol 3-kinase activity17371240
GO:0035005IBA-1-phosphatidylinositol-4-phosphate 3-kinase activity-
GO:0035005TAS-1-phosphatidylinositol-4-phosphate 3-kinase activity-
GO:0035091IEA-phosphatidylinositol binding-
GO ID Evidence Qualifier GO_term References
GO:0006661TAS-phosphatidylinositol biosynthetic process-
GO:0006887TAS-exocytosis17371240
GO:0006897IMP-endocytosis21081650
GO:0007173TAS-epidermal growth factor receptor signaling pathway17371240
GO:0008286TAS-insulin receptor signaling pathway17371240
GO:0014829TAS-vascular smooth muscle contraction17371240
GO:0036092IEA-phosphatidylinositol-3-phosphate biosynthetic process-
GO:0046854IEA-phosphatidylinositol phosphorylation-
GO:0048008TAS-platelet-derived growth factor receptor signaling pathway17371240
GO:0048015IEA-phosphatidylinositol-mediated signaling-
GO:0048268TAS-clathrin coat assembly17371240
GO:0061024TAS-membrane organization-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PIK3C2AFKBP411130420562859 Affinity Capture-MS
PIK3C2AFKBP410857820562859 Affinity Capture-MS
PIK3C2AMLH111043817148452 Affinity Capture-MS
PIK3C2AMLH111130417148452 Affinity Capture-MS
PIK3C2APA2G411107520562859 Affinity Capture-MS
PIK3C2APA2G411130420562859 Affinity Capture-MS
PIK3C2APGK111125120562859 Affinity Capture-MS
PIK3C2APGK111130420562859 Affinity Capture-MS
PMS2PIK3C2A11130417148452 Affinity Capture-MS
PMS2PIK3C2A11140417148452 Affinity Capture-MS
PMS1PIK3C2A11130417148452 Affinity Capture-Western
PMS1PIK3C2A11139117148452 Affinity Capture-Western
STAMBPPIK3C2A11586319615732 Affinity Capture-MS
STAMBPPIK3C2A11130419615732 Affinity Capture-MS
ATG7PIK3C2A11578720562859 Affinity Capture-MS
ATG7PIK3C2A11130420562859 Affinity Capture-MS
ANKFY1PIK3C2A11956420562859 Affinity Capture-MS
ANKFY1PIK3C2A11130420562859 Affinity Capture-MS
TARSPIK3C2A11276020562859 Affinity Capture-MS
TARSPIK3C2A11130420562859 Affinity Capture-MS
TKTPIK3C2A11294120562859 Affinity Capture-MS
TKTPIK3C2A11130420562859 Affinity Capture-MS
MAP1LC3APIK3C2A12413720562859 Affinity Capture-MS
MAP1LC3APIK3C2A11130420562859 Affinity Capture-MS
EIF3APIK3C2A11421020562859 Affinity Capture-MS
EIF3APIK3C2A11130420562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
PIK3C2Ars1544609, rs2040859, rs4356203 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1203729
  • Data Attributes: MGI curated and HomoloGene calculated
No data