AutismKB 2.0

Annotation Details for PITX1


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Basic Information Top
Gene Symbol:PITX1 ( BFT,CCF,POTX,PTX1 )
Gene Full Name: paired-like homeodomain 1
Band: 5q31.1
Quick LinksEntrez ID:5307; OMIM: 602149; Uniprot ID:PITX1_HUMAN; ENSEMBL ID: ENSG00000069011; HGNC ID: 9004
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus17984056
GO:0005667IEA-transcription factor complex-
GO:0005730IDA-nucleolus-
GO:0005737IEA-cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0001077IEA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0001085IPI-RNA polymerase II transcription factor binding26612202
GO:0001190IEA-transcriptional activator activity, RNA polymerase II transcription factor binding-
GO:0003700ISS-transcription factor activity, sequence-specific DNA binding-
GO:0005515IPI-protein binding16189514
GO ID Evidence Qualifier GO_term References
GO:0001501TAS-skeletal system development9070926
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0009653TAS-anatomical structure morphogenesis9070926
GO:0014707IEA-branchiomeric skeletal muscle development-
GO:0021983IEA-pituitary gland development-
GO:0035116IEA-embryonic hindlimb morphogenesis-
GO:0045892IEA-negative regulation of transcription, DNA-templated-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0048625IEA-myoblast fate commitment-
GO:0051216IEA-cartilage development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PITX1DVL311132416189514 Two-hybrid
PITX1DVL310819016189514 Two-hybrid
PITX1EGR111132410082522 Reconstituted Complex
PITX1EGR110827810082522 Reconstituted Complex
PITX1NR5A111132410369682 Reconstituted Complex
PITX1NR5A110879210369682 Reconstituted Complex
PITX1SMAD311026318339718 Affinity Capture-Western
PITX1SMAD311132418339718 Affinity Capture-Western
POU1F1PITX11114458755540 Reconstituted Complex; Two-hybrid
POU1F1PITX11113248755540 Reconstituted Complex; Two-hybrid
RBPMSPITX111622016189514 Two-hybrid
RBPMSPITX111132416189514 Two-hybrid
RHOXF2PITX112411916189514 Two-hybrid
RHOXF2PITX111132416189514 Two-hybrid
SMARCA2PITX111132417043312 Reconstituted Complex
SMARCA2PITX111247917043312 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107374
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060421-3623'