AutismKB 2.0

Annotation Details for PLA2G1B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PLA2G1B ( MGC119834,MGC119835,PLA2,PLA2A,PPLA2 )
Gene Full Name: phospholipase A2, group IB (pancreas)
Band: 12q24.31
Quick LinksEntrez ID:5319; OMIM: 172410; Uniprot ID:PA21B_HUMAN; ENSEMBL ID: ENSG00000170890; HGNC ID: 9030
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space7060561
GO:0005829IDA-cytosol-
GO:0009986IDA-cell surface1918029
GO:0030141IEA-secretory granule-
GO ID Evidence Qualifier GO_term References
GO:0004623IDA-phospholipase A2 activity1918029
GO:0004623TAS-phospholipase A2 activity-
GO:0005102IDA-receptor binding1918029
GO:0005102IPI-receptor binding7721806
GO:0005509IDA-calcium ion binding7060561
GO:0032052ISS-bile acid binding7060561
GO:0047498IDA-calcium-dependent phospholipase A2 activity7060561
GO ID Evidence Qualifier GO_term References
GO:0000187ISS-activation of MAPK activity15528384
GO:0002227IDA-innate immune response in mucosa12860195
GO:0002446ISS-neutrophil mediated immunity16005851
GO:0006633IDA-fatty acid biosynthetic process1918029
GO:0006654TAS-phosphatidic acid biosynthetic process-
GO:0007015TAS-actin filament organization9886417
GO:0007165TAS-signal transduction9886417
GO:0010524ISS-positive regulation of calcium ion transport into cytosol15528384
GO:0015758ISS-glucose transport1918029
GO:0019370ISS-leukotriene biosynthetic process16005851
GO:0019731IDA-antibacterial humoral response12860195
GO:0030593ISS-neutrophil chemotaxis16005851
GO:0032431TAS-activation of phospholipase A2 activity17981679
GO:0032637ISS-interleukin-8 production15528384
GO:0032869ISS-cellular response to insulin stimulus1918029
GO:0035556ISS-intracellular signal transduction15528384
GO:0036148TAS-phosphatidylglycerol acyl-chain remodeling-
GO:0036149TAS-phosphatidylinositol acyl-chain remodeling-
GO:0036150TAS-phosphatidylserine acyl-chain remodeling-
GO:0036151TAS-phosphatidylcholine acyl-chain remodeling-
GO:0036152TAS-phosphatidylethanolamine acyl-chain remodeling-
GO:0044240IDA-multicellular organismal lipid catabolic process7060561
GO:0045740IDA-positive regulation of DNA replication1918029
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter15528384
GO:0046470IDA-phosphatidylcholine metabolic process7060561
GO:0048146IC-positive regulation of fibroblast proliferation1918029
GO:0050482TAS-arachidonic acid secretion12423354
GO:0050714TAS-positive regulation of protein secretion17981679
GO:0050778ISS-positive regulation of immune response16005851
GO:0050830IDA-defense response to Gram-positive bacterium12860195
GO:0051092ISS-positive regulation of NF-kappaB transcription factor activity15528384
GO:0061844IDA-antimicrobial humoral immune response mediated by antimicrobial peptide12860195
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PLA2G2APLA2G1B1113367721806 Reconstituted Complex
PLA2G2APLA2G1B1113377721806 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
PLA2G1Brs11065084 Gene overview in AlzGene
No data
Gene Symbol Poly Names Gene overview in SZGene
PLA2G1BsPLA2_TTAn Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:101842
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070117-1'