AutismKB 2.0

Annotation Details for PLAT


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Basic Information Top
Gene Symbol:PLAT ( DKFZp686I03148,T-PA,TPA )
Gene Full Name: plasminogen activator, tissue
Band: 8p11.21
Quick LinksEntrez ID:5327; OMIM: 173370; Uniprot ID:TPA_HUMAN; ENSEMBL ID: ENSG00000104368; HGNC ID: 9051
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IEA-extracellular space-
GO:0005737IDA-cytoplasm1632457
GO:0009986IDA-cell surface1632457
GO:0030141IEA-secretory granule-
GO:0031012IDANOTextracellular matrix1632457
GO:0045177IEA-apical part of cell-
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0001948TAS-glycoprotein binding8186264
GO:0004252IDA-serine-type endopeptidase activity1695900
GO:0004252TAS-serine-type endopeptidase activity-
GO:0005102IPI-receptor binding8186264
GO:0005515IPI-protein binding2503541
GO:0051219IPI-phosphoprotein binding8186264
GO ID Evidence Qualifier GO_term References
GO:0001666IEA-response to hypoxia-
GO:0006464TAS-cellular protein modification process3087818
GO:0006508TAS-proteolysis3087818
GO:0007596TAS-blood coagulation3839198
GO:0014909IEA-smooth muscle cell migration-
GO:0031639IDA-plasminogen activation12694198
GO:0042730TAS-fibrinolysis-
GO:0045861IDA-negative regulation of proteolysis1695900
GO:0048008IEA-platelet-derived growth factor receptor signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PLATANXA210679912468550 Reconstituted Complex
PLATANXA211134312468550 Reconstituted Complex
PLATCALR1113439359841 Reconstituted Complex
PLATCALR1072629359841 Reconstituted Complex
PLATF211134310543954 Co-crystal Structure
PLATF210844710543954 Co-crystal Structure
PLATF1011134311371191 Reconstituted Complex
PLATF1010845711371191 Reconstituted Complex
PLATFGA1113433088041 11170397 Reconstituted Complex
PLATFGA1085343088041 11170397 Reconstituted Complex
PLATFN11113438360181 Reconstituted Complex
PLATFN11086218360181 Reconstituted Complex
PLATHMGB11113438366113 Co-purification
PLATHMGB11093898366113 Co-purification
PLATKRT81100549988531 Reconstituted Complex
PLATKRT81113439988531 Reconstituted Complex
PLATLAMA511010510956663 Reconstituted Complex
PLATLAMA511134310956663 Reconstituted Complex
PLATLRP11102151502153 10632583 Reconstituted Complex
PLATLRP11113431502153 10632583 Reconstituted Complex
PLATSERPINE11113432110366 Reconstituted Complex
PLATSERPINE11110912110366 Reconstituted Complex
PLATSERPINA51111352551064 Reconstituted Complex
PLATSERPINA51113432551064 Reconstituted Complex
PLATSERPINI111134312354288 Biochemical Activity; Reconstituted Complex
PLATSERPINI111129212354288 Biochemical Activity; Reconstituted Complex
PLAUPLAT1113437721771 Reconstituted Complex
PLAUPLAT1113447721771 Reconstituted Complex
LAMA1PLAT1297928360181 Reconstituted Complex
LAMA1PLAT1113438360181 Reconstituted Complex
CLEC3BPLAT11134312694198 Reconstituted Complex
CLEC3BPLAT11297812694198 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
PLATrs1058720, rs2020923, rs2070711, rs4646972 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:97610
  • Data Attributes: MGI curated and HomoloGene calculated
No data