AutismKB 2.0

Annotation Details for PLG


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Basic Information Top
Gene Symbol:PLG ( DKFZp779M0222 )
Gene Full Name: plasminogen
Band: 6q26
Quick LinksEntrez ID:5340; OMIM: 173350; Uniprot ID:PLMN_HUMAN; ENSEMBL ID: ENSG00000122194; HGNC ID: 9071
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space6216475
GO:0005886TAS-plasma membrane-
GO:0009986IDA-cell surface14699093
GO:0031093TAS-platelet alpha granule lumen-
GO:0031232IDA-extrinsic component of external side of plasma membrane14699093
GO:0044218IDA-other organism cell membrane17307854
GO:0070062IDA-extracellular exosome19199708
GO:0072562IDA-blood microparticle22516433
GO ID Evidence Qualifier GO_term References
GO:0004175IDA-endopeptidase activity9603964
GO:0004252IDA-serine-type endopeptidase activity14688145
GO:0004252IMP-serine-type endopeptidase activity18070902
GO:0004252TAS-serine-type endopeptidase activity-
GO:0005102IPI-receptor binding20028034
GO:0005515IPI-protein binding134998
GO:0008236TAS-serine-type peptidase activity24263861
GO:0019899IPI-enzyme binding12666133
GO:0019900IPI-kinase binding24196407
GO:0019904IPI-protein domain specific binding9786936
GO:0034185IPI-apolipoprotein binding16480936
GO:0051087IPI-chaperone binding17307854
GO:1904854IPI-proteasome core complex binding17849409
GO:1990405IPI-protein antigen binding17849409
GO ID Evidence Qualifier GO_term References
GO:0002576TAS-platelet degranulation-
GO:0006508IDA-proteolysis9603964
GO:0006508IMP-proteolysis18070902
GO:0007596IMP-blood coagulation1986355
GO:0008285TAS-negative regulation of cell proliferation8910613
GO:0010812IDA-negative regulation of cell-substrate adhesion14699093
GO:0022617IDA-extracellular matrix disassembly14699093
GO:0022617TAS-extracellular matrix disassembly-
GO:0042730IDA-fibrinolysis14688145
GO:0042730TAS-fibrinolysis-
GO:0044267TAS-cellular protein metabolic process-
GO:0048771IEA-tissue remodeling-
GO:0051702IDA-interaction with symbiont12818429
GO:0051918IDA-negative regulation of fibrinolysis14726399
GO:0051919IDA-positive regulation of fibrinolysis6438154
GO:0052182IDA-modification by host of symbiont morphology or physiology via secreted substance14688145
GO:0052182IMP-modification by host of symbiont morphology or physiology via secreted substance18070902
GO:0052213IDA-interaction with symbiont via secreted substance involved in symbiotic interaction19270100
GO:2000048TAS-negative regulation of cell-cell adhesion mediated by cadherin17203182
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PLGC71071917814888 Reconstituted Complex
PLGC71113567814888 Reconstituted Complex
PLGCHGA10753811342539 Biochemical Activity
PLGCHGA11135611342539 Biochemical Activity
PLGCPB21077531939207 Co-purification
PLGCPB21113561939207 Co-purification
PLGENO111135611169399 Reconstituted Complex
PLGENO110833811169399 Reconstituted Complex
PLGF31113569490681 Reconstituted Complex
PLGF31084519490681 Reconstituted Complex
PLGF1011135611371191 Reconstituted Complex
PLGF1010845711371191 Reconstituted Complex
PLGFN11113568360181 Reconstituted Complex
PLGFN11086218360181 Reconstituted Complex
PLGHMGB11113561909331 Reconstituted Complex
PLGHMGB11093891909331 Reconstituted Complex
PLGIGFBP31113569688635 Co-purification; Reconstituted Complex
PLGIGFBP31097079688635 Co-purification; Reconstituted Complex
PLGKNG11100269428707 Reconstituted Complex
PLGKNG11113569428707 Reconstituted Complex
PLGLAMA511135610956663 Reconstituted Complex
PLGLAMA511010510956663 Reconstituted Complex
PLGSERPINE111135611113116 Reconstituted Complex
PLGSERPINE111109111113116 Reconstituted Complex
PLGPAPPA1111047586586 Biochemical Activity
PLGPAPPA1113567586586 Biochemical Activity
SERPINF2PLG111356158022 2437112 Biochemical Activity; Reconstituted Complex
SERPINF2PLG111360158022 2437112 Biochemical Activity; Reconstituted Complex
THBS1PLG1113562522013 6438154 Reconstituted Complex
THBS1PLG1129152522013 6438154 Reconstituted Complex
SPARCPLG1113567982919 Reconstituted Complex
SPARCPLG1125607982919 Reconstituted Complex
LAMA1PLG1113568360181 Reconstituted Complex
LAMA1PLG1297928360181 Reconstituted Complex
S100A10PLG11218911939791 Far Western
S100A10PLG11135611939791 Far Western
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
PLGrs11060, rs1130656, rs3757019 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:97620
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-1411'