AutismKB 2.0

Annotation Details for PLP1


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Basic Information Top
Gene Symbol:PLP1 ( HLD1,MMPL,PLP,PLP/DM20,PMD,SPG2 )
Gene Full Name: proteolipid protein 1
Band: Xq22.2
Quick LinksEntrez ID:5354; OMIM: 300401; Uniprot ID:MYPR_HUMAN; ENSEMBL ID: ENSG00000123560; HGNC ID: 9086
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IDA-plasma membrane24103481
GO:0016021IEA-integral component of membrane-
GO:0043209IEA-myelin sheath-
GO ID Evidence Qualifier GO_term References
GO:0005198TAS-structural molecule activity2479017
GO:0005515IPI-protein binding25416956
GO:0019911IEA-structural constituent of myelin sheath-
GO ID Evidence Qualifier GO_term References
GO:0006954IEA-inflammatory response-
GO:0007229IEA-integrin-mediated signaling pathway-
GO:0007268TAS-chemical synaptic transmission2479017
GO:0008366TAS-axon ensheathment2479017
GO:0010628IEA-positive regulation of gene expression-
GO:0014002IEA-astrocyte development-
GO:0021762IEP-substantia nigra development22926577
GO:0022010IEA-central nervous system myelination-
GO:0042759IEA-long-chain fatty acid biosynthetic process-
GO:0048469IEA-cell maturation-
GO:0061564IEA-axon development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PLP1MBP1103252467009 6083474 Co-purification; Reconstituted Complex
PLP1MBP1113682467009 6083474 Co-purification; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
PLP1rs10521502, rs1126707, rs2233696, rs471416, rs475827, rs532117 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:97623
  • Data Attributes: MGI curated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-001202-1'