Gene Symbol:	PLXNB1 ( KIAA0407,MGC149167,PLEXIN-B1,PLXN5,SEP )
Gene Full Name:	plexin B1
Band:	3p21.31
Quick Links	Entrez ID:5364; OMIM: 601053; Uniprot ID:PLXB1_HUMAN; ENSEMBL ID: ENSG00000164050; HGNC ID: 9103
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0002116	IDA	-	semaphorin receptor complex	19843518
GO:0002116	TAS	-	semaphorin receptor complex	19909241
GO:0005576	IEA	-	extracellular region	-
GO:0005622	IEA	-	intracellular	-
GO:0005886	TAS	-	plasma membrane	-
GO:0005887	IDA	-	integral component of plasma membrane	19843518
GO:0005887	NAS	-	integral component of plasma membrane	10520995

GO ID	Evidence	Qualifier	GO_term	References
GO:0004872	TAS	-	receptor activity	8570614
GO:0004888	NAS	-	transmembrane signaling receptor activity	10520995
GO:0005096	TAS	-	GTPase activator activity	-
GO:0005515	IPI	-	protein binding	12730235
GO:0017154	IDA	-	semaphorin receptor activity	19843518
GO:0017154	TAS	-	semaphorin receptor activity	10520995
GO:0030215	TAS	-	semaphorin receptor binding	10520995
GO:0032794	ISS	-	GTPase activating protein binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0007162	IDA	-	negative regulation of cell adhesion	15218527
GO:0007165	TAS	-	signal transduction	8570614
GO:0008360	IDA	-	regulation of cell shape	19843518
GO:0014068	ISS	-	positive regulation of phosphatidylinositol 3-kinase signaling	-
GO:0016477	NAS	-	cell migration	10520995
GO:0033689	ISS	-	negative regulation of osteoblast proliferation	-
GO:0035556	NAS	-	intracellular signal transduction	10520995
GO:0043087	IBA	-	regulation of GTPase activity	-
GO:0043547	ISS	-	positive regulation of GTPase activity	-
GO:0043931	ISS	-	ossification involved in bone maturation	-
GO:0048675	IBA	-	axon extension	-
GO:0048812	ISS	-	neuron projection morphogenesis	-
GO:0050772	IBA	-	positive regulation of axonogenesis	-
GO:0051493	IDA	-	regulation of cytoskeleton organization	19843518
GO:0071526	IDA	-	semaphorin-plexin signaling pathway	15218527
GO:1900220	ISS	-	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis	-

Gene Symbol	Interactant	Interaction ID	References	Description
PLXNB1	AKT1	106710	19805522	Affinity Capture-Western
PLXNB1	AKT1	111377	19805522	Affinity Capture-Western
PLXNB1	RHOA	106880	19805522	Affinity Capture-Western
PLXNB1	RHOA	111377	19805522	Affinity Capture-Western
PLXNB1	RND3	106883	12730235	Reconstituted Complex
PLXNB1	RND3	111377	12730235	Reconstituted Complex
PLXNB1	GRB2	109142	19805522	Affinity Capture-Western
PLXNB1	GRB2	111377	19805522	Affinity Capture-Western
PLXNB1	PLCG1	111351	19805522	Affinity Capture-Western
PLXNB1	PLCG1	111377	19805522	Affinity Capture-Western
PLXNB1	PLCG2	111352	19805522	Affinity Capture-Western
PLXNB1	PLCG2	111377	19805522	Affinity Capture-Western
SEMA4D	PLXNB1	115766	11937491	Affinity Capture-Western
SEMA4D	PLXNB1	111377	11937491	Affinity Capture-Western
ARHGEF11	PLXNB1	115164	12123608 12183458 12220504 12730235	Affinity Capture-Western; Co-localization; Two-hybrid
ARHGEF11	PLXNB1	111377	12123608 12183458 12220504 12730235	Affinity Capture-Western; Co-localization; Two-hybrid
ARHGEF12	PLXNB1	116945	12220504	Affinity Capture-Western; Two-hybrid
ARHGEF12	PLXNB1	111377	12220504	Affinity Capture-Western; Two-hybrid
RND1	PLXNB1	118113	12730235	Affinity Capture-Western; Reconstituted Complex
RND1	PLXNB1	111377	12730235	Affinity Capture-Western; Reconstituted Complex
RND2	PLXNB1	113810	12730235	Reconstituted Complex
RND2	PLXNB1	111377	12730235	Reconstituted Complex

AutismKB 2.0

Annotation Details for PLXNB1