AutismKB 2.0

Annotation Details for PLXNB3


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Basic Information Top
Gene Symbol:PLXNB3 ( FLJ76953,PLEXB3,PLEXR,PLXN6 )
Gene Full Name: plexin B3
Band: Xq28
Quick LinksEntrez ID:5365; OMIM: 300214; Uniprot ID:PLXB3_HUMAN; ENSEMBL ID: ENSG00000198753; HGNC ID: 9105
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0009986IDA-cell surface16122393
GO:0016021IEA-integral component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15184888
GO:0017154IDA-semaphorin receptor activity15218527
GO:0019904IPI-protein domain specific binding15218527
GO:0051022IEA-Rho GDP-dissociation inhibitor binding-
GO:0098632IPI-protein binding involved in cell-cell adhesion16122393
GO ID Evidence Qualifier GO_term References
GO:0001938IMP-positive regulation of endothelial cell proliferation19850054
GO:0007156IDA-homophilic cell adhesion via plasma membrane adhesion molecules16122393
GO:0007162IDA-negative regulation of cell adhesion15218527
GO:0008360IBA-regulation of cell shape-
GO:0010593ISS-negative regulation of lamellipodium assembly-
GO:0010976IDA-positive regulation of neuron projection development16122393
GO:0030336IMP-negative regulation of cell migration20696765
GO:0034260IMP-negative regulation of GTPase activity20696765
GO:0048675IBA-axon extension-
GO:0050772IBA-positive regulation of axonogenesis-
GO:0050918IDA-positive chemotaxis15218527
GO:0060326IDA-cell chemotaxis15218527
GO:0071526IDA-semaphorin-plexin signaling pathway15218527
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ARHGEF11PLXNB311516412123608 12183458 Affinity Capture-Western; Two-hybrid
ARHGEF11PLXNB311137812123608 12183458 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2154240
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-081104-53'