AutismKB 2.0

Annotation Details for POLR2B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:POLR2B ( POL2RB,RPB2,hRPB140,hsRPB2 )
Gene Full Name: polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
Band: 4q12
Quick LinksEntrez ID:5431; OMIM: 180661; Uniprot ID:RPB2_HUMAN; ENSEMBL ID: ENSG00000047315; HGNC ID: 9188
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000784IDAcolocalizes_withnuclear chromosome, telomeric region24270157
GO:0005634IDA-nucleus9852112
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005665IDA-DNA-directed RNA polymerase II, core complex9852112
GO:0016020IDA-membrane19946888
GO ID Evidence Qualifier GO_term References
GO:0001055IBAcontributes_toRNA polymerase II activity-
GO:0003677IEA-DNA binding-
GO:0003682IEA-chromatin binding-
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding17998332
GO:0032549IEA-ribonucleoside binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000398TAS-mRNA splicing, via spliceosome-
GO:0006283TAS-transcription-coupled nucleotide-excision repair-
GO:0006351TAS-transcription, DNA-templated-
GO:0006366IDA-transcription from RNA polymerase II promoter9852112
GO:0006366TAS-transcription from RNA polymerase II promoter-
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0006368TAS-transcription elongation from RNA polymerase II promoter-
GO:0006370TAS-7-methylguanosine mRNA capping-
GO:0008543TAS-fibroblast growth factor receptor signaling pathway-
GO:0016070TAS-RNA metabolic process-
GO:0035019TAS-somatic stem cell population maintenance-
GO:0042795TAS-snRNA transcription from RNA polymerase II promoter-
GO:0050434TAS-positive regulation of viral transcription-
GO:0060964TAS-regulation of gene silencing by miRNA-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
POLR2BAIRE10682320085707 Affinity Capture-MS
POLR2BAIRE11142720085707 Affinity Capture-MS
POLR2BBTF31114272320128 Reconstituted Complex
POLR2BBTF31071542320128 Reconstituted Complex
POLR2BGTF2F110921717643375 Affinity Capture-MS
POLR2BGTF2F111142717643375 Affinity Capture-MS
POLR2BGTF2F210921817643375 Affinity Capture-MS
POLR2BGTF2F211142717643375 Affinity Capture-MS
POLR2BNEDD411142716055720 Affinity Capture-MS
POLR2BNEDD411081116055720 Affinity Capture-MS
POLR2BPOLR2A11142719240132 Reconstituted Complex
POLR2BPOLR2A11142619240132 Reconstituted Complex
POLR2HPOLR2B1114339201987 17643375 Affinity Capture-MS; Reconstituted Complex
POLR2HPOLR2B1114279201987 17643375 Affinity Capture-MS; Reconstituted Complex
POLR2CPOLR2B1114279201987 Reconstituted Complex
POLR2CPOLR2B1114289201987 Reconstituted Complex
POLR2EPOLR2B1114309201987 Reconstituted Complex
POLR2EPOLR2B1114279201987 Reconstituted Complex
POLR2KPOLR2B1114279201987 Reconstituted Complex
POLR2KPOLR2B1114369201987 Reconstituted Complex
POLR2LPOLR2B1114279201987 Reconstituted Complex
POLR2LPOLR2B1114379201987 Reconstituted Complex
MED19POLR2B12855315175163 Affinity Capture-MS
MED19POLR2B11142715175163 Affinity Capture-MS
MED9POLR2B12040315175163 Affinity Capture-MS
MED9POLR2B11142715175163 Affinity Capture-MS
MED29POLR2B12073415175163 Affinity Capture-MS
MED29POLR2B11142715175163 Affinity Capture-MS
MED28POLR2B11142715175163 Affinity Capture-MS
MED28POLR2B12321915175163 Affinity Capture-MS
MED10POLR2B11142715175163 Affinity Capture-MS
MED10POLR2B12397415175163 Affinity Capture-MS
MED26POLR2B11483115175163 Affinity Capture-MS
MED26POLR2B11142715175163 Affinity Capture-MS
CTDP1POLR2B11459715670829 Reconstituted Complex
CTDP1POLR2B11142715670829 Reconstituted Complex
WWOXPOLR2B11142716055720 Affinity Capture-MS
WWOXPOLR2B11970716055720 Affinity Capture-MS
ITCHPOLR2B12374716055720 Affinity Capture-MS
ITCHPOLR2B11142716055720 Affinity Capture-MS
RUVBL2POLR2B11606717643375 Affinity Capture-MS
RUVBL2POLR2B11142717643375 Affinity Capture-MS
GPN1POLR2B11142717643375 Affinity Capture-MS
GPN1POLR2B11645217643375 Affinity Capture-MS
KDM1APOLR2B11142717643375 Affinity Capture-MS
KDM1APOLR2B11666717643375 Affinity Capture-MS
RPAP1POLR2B11142717643375 Affinity Capture-MS
RPAP1POLR2B11748717643375 Affinity Capture-MS
POLR2GPOLR2B11142717643375 Affinity Capture-MS
POLR2GPOLR2B11143217643375 Affinity Capture-MS
POLR2JPOLR2B11142717643375 Affinity Capture-MS
POLR2JPOLR2B11143517643375 Affinity Capture-MS
TCEA1POLR2B11277917643375 Affinity Capture-MS
TCEA1POLR2B11142717643375 Affinity Capture-MS
RPAP3POLR2B12278317643375 Affinity Capture-MS
RPAP3POLR2B11142717643375 Affinity Capture-MS
RPAP2POLR2B12295917643375 Affinity Capture-MS
RPAP2POLR2B11142717643375 Affinity Capture-MS
RECQL5POLR2B11479719270065 Affinity Capture-MS
RECQL5POLR2B11142719270065 Affinity Capture-MS
ZSCAN1POLR2B11142720211142 Two-hybrid
ZSCAN1POLR2B12982520211142 Two-hybrid
LZTR1POLR2B11142720211142 Two-hybrid
LZTR1POLR2B11385220211142 Two-hybrid
IKBKGPOLR2B11408920211142 Two-hybrid
IKBKGPOLR2B11142720211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2388280
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041008-1'