AutismKB 2.0

Annotation Details for POLR2F


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Basic Information Top
Gene Symbol:POLR2F ( HRBP14.4,POLRF,RPABC2,RPB14.4,RPB6 )
Gene Full Name: polymerase (RNA) II (DNA directed) polypeptide F
Band: 22q13.1
Quick LinksEntrez ID:5435; OMIM: 604414; Uniprot ID:RPAB2_HUMAN; ENSEMBL ID: ENSG00000100142; HGNC ID: 9193
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001650IDA-fibrillar center-
GO:0005634IDA-nucleus9852112
GO:0005654TAS-nucleoplasm-
GO:0005665IDA-DNA-directed RNA polymerase II, core complex9852112
GO:0005666IBA-DNA-directed RNA polymerase III complex-
GO:0005736IBA-DNA-directed RNA polymerase I complex-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0001054IBAcontributes_toRNA polymerase I activity-
GO:0001055IBAcontributes_toRNA polymerase II activity-
GO:0001056IBAcontributes_toRNA polymerase III activity-
GO:0003677IEA-DNA binding-
GO ID Evidence Qualifier GO_term References
GO:0000398TAS-mRNA splicing, via spliceosome-
GO:0006283TAS-transcription-coupled nucleotide-excision repair-
GO:0006351TAS-transcription, DNA-templated-
GO:0006361TAS-transcription initiation from RNA polymerase I promoter-
GO:0006362TAS-transcription elongation from RNA polymerase I promoter-
GO:0006363TAS-termination of RNA polymerase I transcription-
GO:0006366IDA-transcription from RNA polymerase II promoter9852112
GO:0006366TAS-transcription from RNA polymerase II promoter-
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0006368TAS-transcription elongation from RNA polymerase II promoter-
GO:0006370TAS-7-methylguanosine mRNA capping-
GO:0006383IEA-transcription from RNA polymerase III promoter-
GO:0008543TAS-fibroblast growth factor receptor signaling pathway-
GO:0016070TAS-RNA metabolic process-
GO:0032481TAS-positive regulation of type I interferon production-
GO:0035019TAS-somatic stem cell population maintenance-
GO:0042795TAS-snRNA transcription from RNA polymerase II promoter-
GO:0045815TAS-positive regulation of gene expression, epigenetic-
GO:0050434TAS-positive regulation of viral transcription-
GO:0060964TAS-regulation of gene silencing by miRNA-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
POLR2FPOLR3D10712912391170 Affinity Capture-MS
POLR2FPOLR3D11143112391170 Affinity Capture-MS
POLR2FPOLR2A1114269201987 19240132 Reconstituted Complex
POLR2FPOLR2A1114319201987 19240132 Reconstituted Complex
POLR2FPOLR2C1114289201987 Reconstituted Complex
POLR2FPOLR2C1114319201987 Reconstituted Complex
POLR2FPOLR2E1114309201987 Reconstituted Complex
POLR2FPOLR2E1114319201987 Reconstituted Complex
POLR2GPOLR2F1114319201987 Reconstituted Complex
POLR2GPOLR2F1114329201987 Reconstituted Complex
POLR2KPOLR2F1114369201987 Reconstituted Complex
POLR2KPOLR2F1114319201987 Reconstituted Complex
MED19POLR2F12855315175163 Affinity Capture-MS
MED19POLR2F11143115175163 Affinity Capture-MS
MED9POLR2F12040315175163 Affinity Capture-MS
MED9POLR2F11143115175163 Affinity Capture-MS
MED29POLR2F12073415175163 Affinity Capture-MS
MED29POLR2F11143115175163 Affinity Capture-MS
MED10POLR2F12397415175163 Affinity Capture-MS
MED10POLR2F11143115175163 Affinity Capture-MS
MED26POLR2F11483115175163 Affinity Capture-MS
MED26POLR2F11143115175163 Affinity Capture-MS
MED1POLR2F11146515989967 Affinity Capture-Western
MED1POLR2F11143115989967 Affinity Capture-Western
MED30POLR2F12470715989967 Affinity Capture-Western
MED30POLR2F11143115989967 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1349393
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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