AutismKB 2.0

Annotation Details for SSH1


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Basic Information Top
Gene Symbol:SSH1 ( FLJ21928,FLJ38102,KIAA1298,SSH1L )
Gene Full Name: slingshot homolog 1 (Drosophila)
Band: 12q24.11
Quick LinksEntrez ID:54434; OMIM: 606778; Uniprot ID:SSH1_HUMAN; ENSEMBL ID: ENSG00000084112; HGNC ID: 30579
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm14645219
GO:0005829IEA-cytosol-
GO:0005856IEA-cytoskeleton-
GO:0005886IDA-plasma membrane14645219
GO:0030027IEA-lamellipodium-
GO:0030426IEA-growth cone-
GO:0030496IEA-midbody-
GO:0032154IEA-cleavage furrow-
GO ID Evidence Qualifier GO_term References
GO:0003779IDA-actin binding11832213
GO:0004721IDA-phosphoprotein phosphatase activity11832213
GO:0004721IMP-phosphoprotein phosphatase activity19000834
GO:0004725IEA-protein tyrosine phosphatase activity-
GO:0005515IPI-protein binding15159416
GO:0008138IEA-protein tyrosine/serine/threonine phosphatase activity-
GO ID Evidence Qualifier GO_term References
GO:0000902IMP-cell morphogenesis14645219
GO:0006470IMP-protein dephosphorylation11832213
GO:0008064IBA-regulation of actin polymerization or depolymerization-
GO:0010591IBA-regulation of lamellipodium assembly-
GO:0030036IMP-actin cytoskeleton organization11832213
GO:0031915IEA-positive regulation of synaptic plasticity-
GO:0032268IDA-regulation of cellular protein metabolic process19000834
GO:0035335IEA-peptidyl-tyrosine dephosphorylation-
GO:0050770IBA-regulation of axonogenesis-
GO:0071318IDA-cellular response to ATP19000834
GO:0098976IEA-excitatory chemical synaptic transmission-
GO:1901216IEA-positive regulation of neuron death-
GO:1904719IEA-positive regulation of AMPA glutamate receptor clustering-
GO:1904754IEA-positive regulation of vascular associated smooth muscle cell migration-
GO:2000463IEA-positive regulation of excitatory postsynaptic potential-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SSH1ACTB11995011832213 Reconstituted Complex
SSH1ACTB10657511832213 Reconstituted Complex
SSH1DSTN11622311832213 Biochemical Activity
SSH1DSTN11995011832213 Biochemical Activity
Gene Symbol Interactant Interaction ID References Description
SSH1CFL121494615660133 Unphosphorylated SSH-1L interacts with and dephosphorylates cofilin.
SSH1LIMK221494815660133 SSH-1L interacts with and dephosphorylates an unspecified isoform of LIMK2.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2686240
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5909'