AutismKB 2.0

Annotation Details for FBXW5


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Basic Information Top
Gene Symbol:FBXW5 ( DKFZp434B205,Fbw5,MGC20962,RP11-229P13.10 )
Gene Full Name: F-box and WD repeat domain containing 5
Band: 9q34.3
Quick LinksEntrez ID:54461; OMIM: 609072; Uniprot ID:FBXW5_HUMAN; ENSEMBL ID: ENSG00000159069; HGNC ID: 13613
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm21725316
GO:0005829TAS-cytosol-
GO:0019005IDA-SCF ubiquitin ligase complex21725316
GO:0080008IDA-Cul4-RING E3 ubiquitin ligase complex18381890
GO ID Evidence Qualifier GO_term References
GO:0004842EXP-ubiquitin-protein transferase activity19028597
GO:0004842TAS-ubiquitin-protein transferase activity-
GO:0005515IPI-protein binding15070733
GO:0019901IPI-protein kinase binding21725316
GO ID Evidence Qualifier GO_term References
GO:0000209TAS-protein polyubiquitination-
GO:0007088IEA-regulation of mitotic nuclear division-
GO:0010824IMP-regulation of centrosome duplication21725316
GO:0016567IDA-protein ubiquitination18381890
GO:0031146IDA-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process21725316
GO:0043161IDA-proteasome-mediated ubiquitin-dependent protein catabolic process18381890
GO:0043687TAS-post-translational protein modification-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FBXW5DDB111996718381890 Affinity Capture-Western
FBXW5DDB110800918381890 Affinity Capture-Western
FBXW5MDFI11035316189514 Two-hybrid
FBXW5MDFI11996716189514 Two-hybrid
FBXW5TSC111309918381890 Affinity Capture-Western
FBXW5TSC111996718381890 Affinity Capture-Western
FBXW5TSC211310018381890 Affinity Capture-Western
FBXW5TSC211996718381890 Affinity Capture-Western
FBXW5CUL4A11996718381890 Affinity Capture-Western
FBXW5CUL4A11402918381890 Affinity Capture-Western
FBXW5NLK11968518765672 Affinity Capture-Western
FBXW5NLK11996718765672 Affinity Capture-Western
KRTAP4-12FBXW511996716189514 Two-hybrid
KRTAP4-12FBXW512375616189514 Two-hybrid
WDR20FBXW511996719615732 Affinity Capture-MS
WDR20FBXW512488419615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1354731
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2571'