Annotation Details for XRN1


Gene Symbol: | XRN1 ( DKFZp434P0721,DKFZp686B22225,DKFZp686F19113,FLJ41903,SEP1 ) |
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Gene Full Name: | 5'-3' exoribonuclease 1 |
Band: | 3q23 |
Quick Links | Entrez ID:54464; OMIM: 607994; Uniprot ID:XRN1_HUMAN; ENSEMBL ID: ENSG00000114127; HGNC ID: 30654 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000932 | IEA | - | P-body | - |
GO:0005634 | IEA | - | nucleus | - |
GO:0005829 | IDA | - | cytosol | - |
GO:0005829 | TAS | - | cytosol | - |
GO:0005886 | IDA | - | plasma membrane | - |
GO:0016020 | IDA | - | membrane | 19946888 |
GO:0030425 | IEA | - | dendrite | - |
GO:0043025 | IEA | - | neuronal cell body | - |
GO:0045202 | IEA | - | synapse | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0002151 | ISS | - | G-quadruplex RNA binding | - |
GO:0003723 | IDA | - | RNA binding | 22658674 |
GO:0004534 | IMP | - | 5'-3' exoribonuclease activity | 26950371 |
GO:0004534 | ISS | - | 5'-3' exoribonuclease activity | - |
GO:0005515 | IPI | - | protein binding | 15687258 |
GO:0051880 | ISS | - | G-quadruplex DNA binding | - |
GO:0070034 | IC | - | telomerase RNA binding | 26950371 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000956 | IMP | - | nuclear-transcribed mRNA catabolic process | 17545563 |
GO:0016075 | IMP | - | rRNA catabolic process | 20368444 |
GO:0017148 | IEA | - | negative regulation of translation | - |
GO:0032211 | IC | - | negative regulation of telomere maintenance via telomerase | 26950371 |
GO:0033574 | IEA | - | response to testosterone | - |
GO:0043488 | TAS | - | regulation of mRNA stability | - |
GO:0071028 | IMP | - | nuclear mRNA surveillance | 17545563 |
GO:0071044 | IMP | - | histone mRNA catabolic process | 18172165 |
GO:0071409 | IEA | - | cellular response to cycloheximide | - |
GO:0090503 | ISS | - | RNA phosphodiester bond hydrolysis, exonucleolytic | - |
GO:1905795 | IEA | - | cellular response to puromycin | - |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
XRN1 | ALDOA | 106728 | 15231747 | Two-hybrid |
XRN1 | ALDOA | 119970 | 15231747 | Two-hybrid |
XRN1 | CHD4 | 119970 | 15231747 | Two-hybrid |
XRN1 | CHD4 | 107533 | 15231747 | Two-hybrid |
XRN1 | MLH1 | 110438 | 17148452 | Affinity Capture-MS |
XRN1 | MLH1 | 119970 | 17148452 | Affinity Capture-MS |
XRN1 | UPF1 | 119970 | 14527413 | Affinity Capture-Western |
XRN1 | UPF1 | 111908 | 14527413 | Affinity Capture-Western |
XRN1 | SMARCD2 | 112487 | 15231747 | Two-hybrid |
XRN1 | SMARCD2 | 119970 | 15231747 | Two-hybrid |
XRN1 | BAT3 | 119970 | 15231747 | Two-hybrid |
XRN1 | BAT3 | 113647 | 15231747 | Two-hybrid |
XRN1 | PABPC4 | 114296 | 15231747 | Two-hybrid |
XRN1 | PABPC4 | 119970 | 15231747 | Two-hybrid |
XRN1 | AP1G2 | 119970 | 15231747 | Two-hybrid |
XRN1 | AP1G2 | 114420 | 15231747 | Two-hybrid |
XRN1 | CCT5 | 116603 | 15231747 | Two-hybrid |
XRN1 | CCT5 | 119970 | 15231747 | Two-hybrid |
XRN1 | LSM4 | 117336 | 15231747 | Two-hybrid |
XRN1 | LSM4 | 119970 | 15231747 | Two-hybrid |
XRN1 | UPF2 | 117490 | 14527413 | Affinity Capture-Western |
XRN1 | UPF2 | 119970 | 14527413 | Affinity Capture-Western |
UPF3A | XRN1 | 122397 | 14527413 | Affinity Capture-Western |
UPF3A | XRN1 | 119970 | 14527413 | Affinity Capture-Western |
No data |
No data |
- MGI ID: MGI:891964
- Data Attributes: HomoloGene calculated
- ZFIN ID: ZDB-GENE-040426-1203