AutismKB 2.0

Annotation Details for POU1F1


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Basic Information Top
Gene Symbol:POU1F1 ( CPHD1,GHF-1,PIT1,POU1F1a,Pit-1 )
Gene Full Name: POU class 1 homeobox 1
Band: 3p11.2
Quick LinksEntrez ID:5449; OMIM: 173110; Uniprot ID:PIT1_HUMAN; ENSEMBL ID: ENSG00000064835; HGNC ID: 9210
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus26612202
GO:0005667IEA-transcription factor complex-
GO ID Evidence Qualifier GO_term References
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0000981IDA-RNA polymerase II transcription factor activity, sequence-specific DNA binding26612202
GO:0001077IEA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0001085IPI-RNA polymerase II transcription factor binding26612202
GO:0001102IPI-RNA polymerase II activating transcription factor binding9685346
GO:0001105IDA-RNA polymerase II transcription coactivator activity9685346
GO:0003682IEA-chromatin binding-
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding9482665
GO:0003714IEA-transcription corepressor activity-
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0001708IEA-cell fate specification-
GO:0006355IDA-regulation of transcription, DNA-templated11301317
GO:0006366TAS-transcription from RNA polymerase II promoter1487156
GO:0008284IEA-positive regulation of cell proliferation-
GO:0008285TAS-negative regulation of cell proliferation9392392
GO:0008340IEA-determination of adult lifespan-
GO:0030183IEA-B cell differentiation-
GO:0032962IEA-positive regulation of inositol trisphosphate biosynthetic process-
GO:0040018IEA-positive regulation of multicellular organism growth-
GO:0043567IEA-regulation of insulin-like growth factor receptor signaling pathway-
GO:0045893IDA-positive regulation of transcription, DNA-templated9482665
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter9685346
GO:0051169IEA-nuclear transport-
GO:0060133IEA-somatotropin secreting cell development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
POU1F1CREBBP1114459751061 Affinity Capture-Western; Reconstituted Complex
POU1F1CREBBP1077779751061 Affinity Capture-Western; Reconstituted Complex
POU1F1GATA210889410367888 16396960 Affinity Capture-Western; Reconstituted Complex
POU1F1GATA211144510367888 16396960 Affinity Capture-Western; Reconstituted Complex
POU1F1NR3C11114459426156 Reconstituted Complex
POU1F1NR3C11091659426156 Reconstituted Complex
POU1F1JUN1099288663380 Reconstituted Complex
POU1F1JUN1114458663380 Reconstituted Complex
POU1F1PITX11114458755540 Reconstituted Complex; Two-hybrid
POU1F1PITX11113248755540 Reconstituted Complex; Two-hybrid
NCOR1POU1F11114459751061 16030140 Affinity Capture-Western; Reconstituted Complex
NCOR1POU1F11149739751061 16030140 Affinity Capture-Western; Reconstituted Complex
PPARAPOU1F111144511891224 Reconstituted Complex
PPARAPOU1F111146111891224 Reconstituted Complex
PPARGPOU1F111144511891224 Reconstituted Complex
PPARGPOU1F111146411891224 Reconstituted Complex
VDRPOU1F111144511891224 Reconstituted Complex
VDRPOU1F111326411891224 Reconstituted Complex
NR1I2POU1F111144511891224 Reconstituted Complex
NR1I2POU1F111438011891224 Reconstituted Complex
NR1I3POU1F111144511891224 Reconstituted Complex
NR1I3POU1F111529511891224 Reconstituted Complex
MED1POU1F111144516396960 Affinity Capture-Western; Reconstituted Complex
MED1POU1F111146516396960 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97588
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040630-7'