AutismKB 2.0

Annotation Details for POU2F1


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Basic Information Top
Gene Symbol:POU2F1 ( OCT1,OTF1 )
Gene Full Name: POU class 2 homeobox 1
Band: 1q24.2
Quick LinksEntrez ID:5451; OMIM: 164175; Uniprot ID:PO2F1_HUMAN; ENSEMBL ID: ENSG00000143190; HGNC ID: 9212
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus9242494
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005783IDA-endoplasmic reticulum-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0090575IMP-RNA polymerase II transcription factor complex10329190
GO ID Evidence Qualifier GO_term References
GO:0000979IMP-RNA polymerase II core promoter sequence-specific DNA binding10329190
GO:0000983IMP-transcription factor activity, RNA polymerase II core promoter sequence-specific11380252
GO:0003677IDA-DNA binding9199328
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding2341156
GO:0005515IPI-protein binding10629049
GO:0043565IDA-sequence-specific DNA binding7945330
GO ID Evidence Qualifier GO_term References
GO:0006357IC-regulation of transcription from RNA polymerase II promoter10329190
GO:0042795TAS-snRNA transcription from RNA polymerase II promoter-
GO:0045892IDA-negative regulation of transcription, DNA-templated11891224
GO:0045944IGI-positive regulation of transcription from RNA polymerase II promoter11380252
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter11380252
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
POU2F1AR11144710480874 Reconstituted Complex
POU2F1AR10686210480874 Reconstituted Complex
POU2F1BRCA111144711777930 18000219 Affinity Capture-Western
POU2F1BRCA110714011777930 18000219 Affinity Capture-Western
POU2F1CEBPE11144720211142 Two-hybrid
POU2F1CEBPE10748220211142 Two-hybrid
POU2F1CREB111144712391146 Affinity Capture-Western; Reconstituted Complex
POU2F1CREB110777512391146 Affinity Capture-Western; Reconstituted Complex
POU2F1EPRS1114479537509 Far Western; Reconstituted Complex; Two-hybrid
POU2F1EPRS1083729537509 Far Western; Reconstituted Complex; Two-hybrid
POU2F1ESR111144710480874 Reconstituted Complex
POU2F1ESR110840310480874 Reconstituted Complex
POU2F1XRCC610882211279128 17213819 Affinity Capture-Western
POU2F1XRCC611144711279128 17213819 Affinity Capture-Western
POU2F1GAPDH10886812887926 Affinity Capture-Western; Reconstituted Complex
POU2F1GAPDH11144712887926 Affinity Capture-Western; Reconstituted Complex
POU2F1NR3C11114479584182 10480874 10490647 Affinity Capture-Western; Reconstituted Complex
POU2F1NR3C11091659584182 10480874 10490647 Affinity Capture-Western; Reconstituted Complex
POU2F1HCFC11093048454622 9889203 Co-purification; Reconstituted Complex
POU2F1HCFC11114478454622 9889203 Co-purification; Reconstituted Complex
POU2F1HDAC110931519617623 Affinity Capture-Western; Co-localization
POU2F1HDAC111144719617623 Affinity Capture-Western; Co-localization
POU2F1HMGA11094029823775 Far Western; Reconstituted Complex
POU2F1HMGA11114479823775 Far Western; Reconstituted Complex
POU2F1TLX210943620211142 Two-hybrid
POU2F1TLX211144720211142 Two-hybrid
POU2F1HOXC910946520211142 Two-hybrid
POU2F1HOXC911144720211142 Two-hybrid
POU2F1MNAT11114479368058 Reconstituted Complex; Two-hybrid
POU2F1MNAT11104749368058 Reconstituted Complex; Two-hybrid
POU2F1NPAT11092412887926 Affinity Capture-Western
POU2F1NPAT11144712887926 Affinity Capture-Western
POU2F1PBX111144715138251 Reconstituted Complex
POU2F1PBX111112015138251 Reconstituted Complex
POU2F1PGR11126010480874 Reconstituted Complex
POU2F1PGR11144710480874 Reconstituted Complex
POU2F1PKNOX111133315138251 Reconstituted Complex
POU2F1PKNOX111144715138251 Reconstituted Complex
POU2F1POU2AF11114469418884 10541551 11380252 Co-crystal Structure; Reconstituted Complex; Two-hybrid
POU2F1POU2AF11114479418884 10541551 11380252 Co-crystal Structure; Reconstituted Complex; Two-hybrid
PRKACAPOU2F11115531684878 Biochemical Activity
PRKACAPOU2F11114471684878 Biochemical Activity
TBPPOU2F11114478202368 Affinity Capture-Western; Reconstituted Complex
TBPPOU2F11127718202368 Affinity Capture-Western; Reconstituted Complex
SP1POU2F11114478668525 10976766 Reconstituted Complex; Two-hybrid
SP1POU2F11125508668525 10976766 Reconstituted Complex; Two-hybrid
SNAPC4POU2F11114479418884 11856838 Co-crystal Structure; Two-hybrid
SNAPC4POU2F11125059418884 11856838 Co-crystal Structure; Two-hybrid
RXRAPOU2F111144710383413 10480874 Reconstituted Complex
RXRAPOU2F111216810383413 10480874 Reconstituted Complex
TXNRD1POU2F111144710383413 Reconstituted Complex
TXNRD1POU2F111314710383413 Reconstituted Complex
VDRPOU2F111144710383413 Reconstituted Complex
VDRPOU2F111326410383413 Reconstituted Complex
RARAPOU2F111144710480874 Reconstituted Complex
RARAPOU2F111184910480874 Reconstituted Complex
THRAPOU2F111144710480874 Reconstituted Complex
THRAPOU2F111292310480874 Reconstituted Complex
NCOR2POU2F111497411134019 19617623 Affinity Capture-Western; Co-localization; Reconstituted Complex
NCOR2POU2F111144711134019 19617623 Affinity Capture-Western; Co-localization; Reconstituted Complex
XRCC5POU2F111335311279128 12393188 Affinity Capture-Western
XRCC5POU2F111144711279128 12393188 Affinity Capture-Western
POU2F1POU2F111144711583619 Co-crystal Structure
RELAPOU2F111144712019209 Affinity Capture-Western; Reconstituted Complex
RELAPOU2F111190212019209 Affinity Capture-Western; Reconstituted Complex
TNFPOU2F111144712019209 Reconstituted Complex
TNFPOU2F111297912019209 Reconstituted Complex
STIP1POU2F111616212887926 Affinity Capture-Western
STIP1POU2F111144712887926 Affinity Capture-Western
PRKDCPOU2F111157714612514 17213819 Biochemical Activity
PRKDCPOU2F111144714612514 17213819 Biochemical Activity
STAT5BPOU2F111265416025120 Affinity Capture-Western
STAT5BPOU2F111144716025120 Affinity Capture-Western
IRF9POU2F111565220211142 Two-hybrid
IRF9POU2F111144720211142 Two-hybrid
HOXB13POU2F111574420211142 Two-hybrid
HOXB13POU2F111144720211142 Two-hybrid
BRD7POU2F111888320215511 Co-localization
BRD7POU2F111144720215511 Co-localization
No data
Gene Symbol Interactant Interaction ID References Description
POU2F1NPAT0125012887926 -
POU2F1NPAT0326612887926 -
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
POU2F1rs1407814 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:101898
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2422'