AutismKB 2.0

Annotation Details for DDIT4


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Basic Information Top
Gene Symbol:DDIT4 ( Dig2,FLJ20500,REDD-1,REDD1,RP11-442H21.1,RTP801 )
Gene Full Name: DNA-damage-inducible transcript 4
Band: 10q22.1
Quick LinksEntrez ID:54541; OMIM: 607729; Uniprot ID:DDIT4_HUMAN; ENSEMBL ID: ENSG00000168209; HGNC ID: 24944
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IDA-intracellular-
GO:0005737IDA-cytoplasm12453409
GO:0005739IEA-mitochondrion-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0071889IEA-14-3-3 protein binding-
GO ID Evidence Qualifier GO_term References
GO:0001666IDA-response to hypoxia20166753
GO:0001764ISS-neuron migration-
GO:0007420ISS-brain development-
GO:0008283ISS-cell proliferation-
GO:0010801ISS-negative regulation of peptidyl-threonine phosphorylation-
GO:0030182ISS-neuron differentiation-
GO:0032007IMP-negative regulation of TOR signaling20166753
GO:0033137ISS-negative regulation of peptidyl-serine phosphorylation-
GO:0042771ISS-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-
GO:0043241IEA-protein complex disassembly-
GO:0045820IEA-negative regulation of glycolytic process-
GO:0048011ISS-neurotrophin TRK receptor signaling pathway-
GO:0051607IEA-defense response to virus-
GO:0071549IEA-cellular response to dexamethasone stimulus-
GO:0072593IEA-reactive oxygen species metabolic process-
GO:1901216ISS-positive regulation of neuron death-
GO:1902532ISS-negative regulation of intracellular signal transduction-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
C1orf103DDIT412002816169070 Two-hybrid
C1orf103DDIT412090516169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1921997
  • Data Attributes: MGI curated and HomoloGene calculated
No data