Annotation Details for PPEF2

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Basic Information Top

Gene Symbol:	PPEF2 ( PPP7CB )
Gene Full Name:	protein phosphatase, EF-hand calcium binding domain 2
Band:	4q21.1
Quick Links	Entrez ID:5470; OMIM: 602256; Uniprot ID:PPE2_HUMAN; ENSEMBL ID: ENSG00000156194; HGNC ID: 9244
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:3 results
Molecular Function:7 results
Biological Process:7 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0001750	IEA	-	photoreceptor outer segment	-
GO:0001917	IEA	-	photoreceptor inner segment	-
GO:0005737	IEA	-	cytoplasm	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004722	TAS	-	protein serine/threonine phosphatase activity	9326663
GO:0005506	IEA	-	iron ion binding	-
GO:0005509	IEA	-	calcium ion binding	-
GO:0030145	IEA	-	manganese ion binding	-
GO:0030544	IDA	-	Hsp70 protein binding	20674765
GO:0031435	IPI	-	mitogen-activated protein kinase kinase kinase binding	20674765
GO:0051879	IDA	-	Hsp90 protein binding	20674765

GO ID	Evidence	Qualifier	GO_term	References
GO:0006470	TAS	-	protein dephosphorylation	9326663
GO:0007601	IEA	-	visual perception	-
GO:0010801	IDA	-	negative regulation of peptidyl-threonine phosphorylation	20674765
GO:0043405	IC	-	regulation of MAP kinase activity	20674765
GO:0043409	IDA	-	negative regulation of MAPK cascade	20674765
GO:0043506	IC	-	regulation of JUN kinase activity	20674765
GO:0050906	IEA	-	detection of stimulus involved in sensory perception	-

Protein-Protein Interaction

BioGRID:2 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
PPEF2	CALM1	111466	12051765	Reconstituted Complex; Two-hybrid
PPEF2	CALM1	107252	12051765	Reconstituted Complex; Two-hybrid

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:1 results

MGI ID: MGI:1342304
Data Attributes: MGI curated and HomoloGene calculated