AutismKB 2.0

Annotation Details for CTSA


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Basic Information Top
Gene Symbol:CTSA ( GLB2,GSL,NGBE,PPCA,PPGB )
Gene Full Name: cathepsin A
Band: 20q13.12
Quick LinksEntrez ID:5476; OMIM: 613111; Uniprot ID:PPGB_HUMAN; ENSEMBL ID: ENSG00000064601; HGNC ID: 9251
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005654IDA-nucleoplasm-
GO:0005764NAS-lysosome3136930
GO:0005783TAS-endoplasmic reticulum1387645
GO:0016020IDA-membrane19946888
GO:0035578TAS-azurophil granule lumen-
GO:0043202TAS-lysosomal lumen-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0070062IDA-extracellular exosome19056867
GO:0098575TAScolocalizes_withlumenal side of lysosomal membrane20176123
GO ID Evidence Qualifier GO_term References
GO:0004180TAS-carboxypeptidase activity2244901
GO:0004185IMP-serine-type carboxypeptidase activity12505983
GO:0004308TAS-exo-alpha-sialidase activity-
GO:0008047TAS-enzyme activator activity3107551
GO ID Evidence Qualifier GO_term References
GO:0006508IDA-proteolysis12505983
GO:0006687TAS-glycosphingolipid metabolic process-
GO:0006886TAS-intracellular protein transport1387645
GO:0031647IMP-regulation of protein stability12505983
GO:0043085IEA-positive regulation of catalytic activity-
GO:0043312TAS-neutrophil degranulation-
GO:0051603IBA-proteolysis involved in cellular protein catabolic process-
GO:1904714TAS-regulation of chaperone-mediated autophagy20176123
GO:1904715IGI-negative regulation of chaperone-mediated autophagy12505983
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CTSANEU11108319501080 Affinity Capture-Western; Co-fractionation
CTSANEU11114729501080 Affinity Capture-Western; Co-fractionation
CTNNBIP1CTSA12131317353931 Affinity Capture-MS
CTNNBIP1CTSA11147217353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97748
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-537'