AutismKB 2.0

Annotation Details for SLX1A


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Basic Information Top
Gene Symbol:SLX1A ( GIYD1,GIYD2 )
Gene Full Name: SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
Band: 16p11.2
Quick LinksEntrez ID:548593; OMIM: NA; Uniprot ID:SLX1_HUMAN; ENSEMBL ID: ENSG00000132207; HGNC ID: 20922
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0033557IDA-Slx1-Slx4 complex19595721
GO:0033557TAS-Slx1-Slx4 complex24012755
GO ID Evidence Qualifier GO_term References
GO:0004520TAS-endodeoxyribonuclease activity-
GO:0005515IPI-protein binding19595721
GO:0008821IDA-crossover junction endodeoxyribonuclease activity19595721
GO:0017108IDA-5'-flap endonuclease activity19596235
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000724IMP-double-strand break repair via homologous recombination19595721
GO:0006281IMP-DNA repair19595721
GO:0010792IMP-DNA double-strand break processing involved in repair via single-strand annealing19595721
GO:0010833IMP-telomere maintenance via telomere lengthening24012755
GO:0036297TAS-interstrand cross-link repair-
GO:0061820IMP-telomeric D-loop disassembly24012755
GO:0090305IEA-nucleic acid phosphodiester bond hydrolysis-
GO:0090656IMP-t-circle formation24012755
GO:0090656ISS-t-circle formation-
GO:1904357IMP-negative regulation of telomere maintenance via telomere lengthening24012755
GO:1904431ISS-positive regulation of t-circle formation-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018