AutismKB 2.0

Annotation Details for PARP16


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Basic Information Top
Gene Symbol:PARP16 ( C15orf30,FLJ20509,FLJ25281,pART15 )
Gene Full Name: poly (ADP-ribose) polymerase family, member 16
Band: 15q22.31
Quick LinksEntrez ID:54956; OMIM: NA; Uniprot ID:PAR16_HUMAN; ENSEMBL ID: ENSG00000138617; HGNC ID: 26040
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005635IDA-nuclear envelope22701565
GO:0005783IMP-endoplasmic reticulum23103912
GO:0005789IEA-endoplasmic reticulum membrane-
GO:0005829TAS-cytosol-
GO:0016020IDA-membrane19946888
GO:0016021IEA-integral component of membrane-
GO:0071782IMP-endoplasmic reticulum tubular network22701565
GO ID Evidence Qualifier GO_term References
GO:0003950IMP-NAD+ ADP-ribosyltransferase activity22701565
GO:0003950TAS-NAD+ ADP-ribosyltransferase activity-
GO:0005515IPI-protein binding22701565
GO:0019900IPI-kinase binding23103912
GO:0043539IMP-protein serine/threonine kinase activator activity23103912
GO ID Evidence Qualifier GO_term References
GO:0006471IMP-protein ADP-ribosylation22701565
GO:0006987IMP-activation of signaling protein activity involved in unfolded protein response23103912
GO:0030968IMP-endoplasmic reticulum unfolded protein response23103912
GO:0034356TAS-NAD biosynthesis via nicotinamide riboside salvage pathway-
GO:0060548IMP-negative regulation of cell death23103912
GO:0070213IMP-protein auto-ADP-ribosylation22701565
GO:0071902IMP-positive regulation of protein serine/threonine kinase activity23103912
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2446133
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018