AutismKB 2.0

Annotation Details for TESC


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Basic Information Top
Gene Symbol:TESC ( CHP3,FLJ20607,TSC )
Gene Full Name: tescalcin
Band: 12q24.22
Quick LinksEntrez ID:54997; OMIM: 611585; Uniprot ID:TESC_HUMAN; ENSEMBL ID: ENSG00000088992; HGNC ID: 26065
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001726ISS-ruffle-
GO:0005634IDA-nucleus17717601
GO:0005634ISS-nucleus-
GO:0005737IDA-cytoplasm18321853
GO:0005829IDA-cytosol-
GO:0005886IDA-plasma membrane18321853
GO:0030027IDA-lamellipodium11696366
GO:0032587IEA-ruffle membrane-
GO ID Evidence Qualifier GO_term References
GO:0000287ISS-magnesium ion binding-
GO:0004860IEA-protein kinase inhibitor activity-
GO:0005509IDA-calcium ion binding11696366
GO:0005515IPI-protein binding11696366
GO:0019212ISS-phosphatase inhibitor activity-
GO:0042803ISS-protein homodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0006469IEA-negative regulation of protein kinase activity-
GO:0008285IMP-negative regulation of cell proliferation17717601
GO:0008584IEA-male gonad development-
GO:0010628IMP-positive regulation of gene expression17717601
GO:0030219IEA-megakaryocyte differentiation-
GO:0030854IDA-positive regulation of granulocyte differentiation20060826
GO:0032417IDA-positive regulation of sodium:proton antiporter activity18321853
GO:0033628IMP-regulation of cell adhesion mediated by integrin17717601
GO:0045654IMP-positive regulation of megakaryocyte differentiation17717601
GO:0045893IMP-positive regulation of transcription, DNA-templated17717601
GO:0050821IDA-protein stabilization18321853
GO:0051604IDA-protein maturation18321853
GO:0071300IDA-cellular response to retinoic acid20060826
GO:0072661IDA-protein targeting to plasma membrane18321853
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TESCSLC9A111243811696366 12809501 Affinity Capture-Western; Far Western; Reconstituted Complex
TESCSLC9A112033011696366 12809501 Affinity Capture-Western; Far Western; Reconstituted Complex
TESCDYNLT311285016189514 Two-hybrid
TESCDYNLT312033016189514 Two-hybrid
TESCHMG20A11564316189514 Affinity Capture-Western; Two-hybrid
TESCHMG20A12033016189514 Affinity Capture-Western; Two-hybrid
TESCRAI111596616189514 Two-hybrid
TESCRAI112033016189514 Two-hybrid
CCDC91TESC12058416189514 Two-hybrid
CCDC91TESC12033016189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1930803
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2632'