AutismKB 2.0

Annotation Details for PPP1R8


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Basic Information Top
Gene Symbol:PPP1R8 ( ARD-1,ARD1,NIPP-1,NIPP1,PRO2047 )
Gene Full Name: protein phosphatase 1, regulatory (inhibitor) subunit 8
Band: 1p35.3
Quick LinksEntrez ID:5511; OMIM: 602636; Uniprot ID:PP1R8_HUMAN; ENSEMBL ID: ENSG00000117751; HGNC ID: 9296
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634TAS-nucleus7499293
GO:0005654IDA-nucleoplasm-
GO:0005681IEA-spliceosomal complex-
GO:0005737IEA-cytoplasm-
GO:0016607IDA-nuclear speck11739654
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003723TAS-RNA binding9153239
GO:0003729IBA-mRNA binding-
GO:0004519IEA-endonuclease activity-
GO:0004865TAS-protein serine/threonine phosphatase inhibitor activity7499293
GO:0005515IPI-protein binding11739654
GO:0008995TAS-ribonuclease E activity9153239
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0006397IEA-mRNA processing-
GO:0006401TAS-RNA catabolic process9153239
GO:0008283IEA-cell proliferation-
GO:0008380IEA-RNA splicing-
GO:0035308IBA-negative regulation of protein dephosphorylation-
GO:0043086IEA-negative regulation of catalytic activity-
GO:0090501IEA-RNA phosphodiester bond hydrolysis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PPP1R8CRMP110779016169070 Two-hybrid
PPP1R8CRMP111150316169070 Two-hybrid
PPP1R8EZH211150317804093 Affinity Capture-Western; Reconstituted Complex
PPP1R8EZH210844617804093 Affinity Capture-Western; Reconstituted Complex
PPP1R8GBP210890416169070 Two-hybrid
PPP1R8GBP211150316169070 Two-hybrid
PPP1R8HDAC210931612788942 Affinity Capture-Western; Reconstituted Complex
PPP1R8HDAC211150312788942 Affinity Capture-Western; Reconstituted Complex
PPP1R8LYN11024511104670 Biochemical Activity
PPP1R8LYN11150311104670 Biochemical Activity
PPP1R8NME211150317353931 Affinity Capture-MS
PPP1R8NME211089517353931 Affinity Capture-MS
PPP1R8PPP1CA11150310637318 12788942 Reconstituted Complex
PPP1R8PPP1CA11149310637318 12788942 Reconstituted Complex
PPP1R8PPP1CB11149417353931 Affinity Capture-MS
PPP1R8PPP1CB11150317353931 Affinity Capture-MS
PPP1R8PPP1CC11149511104670 Reconstituted Complex
PPP1R8PPP1CC11150311104670 Reconstituted Complex
PRKACAPPP1R81115539407077 Biochemical Activity
PRKACAPPP1R81115039407077 Biochemical Activity
SF3B1PPP1R811150312105215 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SF3B1PPP1R811701712105215 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
EEDPPP1R811426512788942 17804093 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
EEDPPP1R811150312788942 17804093 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
C14orf1PPP1R811633216169070 Two-hybrid
C14orf1PPP1R811150316169070 Two-hybrid
C7orf64PPP1R811150316169070 Two-hybrid
C7orf64PPP1R812385516169070 Two-hybrid
STC2PPP1R811417216169070 Two-hybrid
STC2PPP1R811150316169070 Two-hybrid
SETDB1PPP1R811520216169070 Two-hybrid
SETDB1PPP1R811150316169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2140494
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060503-681'