AutismKB 2.0

Annotation Details for PPP2R2A


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Basic Information Top
Gene Symbol:PPP2R2A ( B55A,B55ALPHA,DKFZp686N05117,FLJ26613,FLJ41727,MGC52248,PR52A,PR55A )
Gene Full Name: protein phosphatase 2, regulatory subunit B, alpha
Band: 8p21.2
Quick LinksEntrez ID:5520; OMIM: 604941; Uniprot ID:2ABA_HUMAN; ENSEMBL ID: ENSG00000221914; HGNC ID: 9304
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000159IDA-protein phosphatase type 2A complex1849734
GO:0005654TAS-nucleoplasm-
GO:0005829IBA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004722IDA-protein serine/threonine phosphatase activity1849734
GO:0004722TAS-protein serine/threonine phosphatase activity-
GO:0005515IPI-protein binding9847399
GO:0019888TAS-protein phosphatase regulator activity1849734
GO:0032403IEA-protein complex binding-
GO:0048156IEA-tau protein binding-
GO:0051721IEA-protein phosphatase 2A binding-
GO ID Evidence Qualifier GO_term References
GO:0000086TAS-G2/M transition of mitotic cell cycle-
GO:0000184TAS-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-
GO:0000278IBA-mitotic cell cycle-
GO:0006470IDA-protein dephosphorylation1849734
GO:0007084TAS-mitotic nuclear envelope reassembly-
GO:0032502IBA-developmental process-
GO:0043278IEA-response to morphine-
GO:0050790IEA-regulation of catalytic activity-
GO:0070262IBA-peptidyl-serine dephosphorylation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PPP2R2AATR10702710608806 Protein-peptide
PPP2R2AATR11151210608806 Protein-peptide
PPP2R2AEIF4EBP111151216899564 Affinity Capture-Western
PPP2R2AEIF4EBP110829316899564 Affinity Capture-Western
PPP2R2AMTOR11151210200280 Reconstituted Complex
PPP2R2AMTOR10875710200280 Reconstituted Complex
PPP2R2AMLH111043817148452 Affinity Capture-MS
PPP2R2AMLH111151217148452 Affinity Capture-MS
PPP2R2APPP2CA1115121328247 18782753 Affinity Capture-MS; Co-purification; Reconstituted Complex
PPP2R2APPP2CA1115071328247 18782753 Affinity Capture-MS; Co-purification; Reconstituted Complex
PPP2R2APPP2CB11151218782753 Affinity Capture-MS
PPP2R2APPP2CB11150818782753 Affinity Capture-MS
PPP2R2APPP2R1A11151212370081 18782753 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
PPP2R2APPP2R1A11151012370081 18782753 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
PPP2R2APPP2R1B1115111328247 12370081 Reconstituted Complex
PPP2R2APPP2R1B1115121328247 12370081 Reconstituted Complex
TGFBR1PPP2R2A1115129774674 Affinity Capture-Western; Reconstituted Complex
TGFBR1PPP2R2A1129049774674 Affinity Capture-Western; Reconstituted Complex
RPS6KB1PPP2R2A11151210200280 16899564 Affinity Capture-Western
RPS6KB1PPP2R2A11211210200280 16899564 Affinity Capture-Western
RRN3PPP2R2A11151215004009 Reconstituted Complex
RRN3PPP2R2A12010215004009 Reconstituted Complex
FAM107APPP2R2A11151217353931 Affinity Capture-MS
FAM107APPP2R2A11634117353931 Affinity Capture-MS
TCEAL1PPP2R2A11151217353931 Affinity Capture-MS
TCEAL1PPP2R2A11474517353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1919228
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5474'