AutismKB 2.0

Annotation Details for HES6


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Basic Information Top
Gene Symbol:HES6 ( HES-6,bHLHb41,bHLHc23 )
Gene Full Name: hairy and enhancer of split 6 (Drosophila)
Band: 2q37.3
Quick LinksEntrez ID:55502; OMIM: 610331; Uniprot ID:HES6_HUMAN; ENSEMBL ID: ENSG00000144485; HGNC ID: 18254
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005667ISS-transcription factor complex10851137
GO ID Evidence Qualifier GO_term References
GO:0000977IEA-RNA polymerase II regulatory region sequence-specific DNA binding-
GO:0001227IEA-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding10851137
GO:0003712ISS-transcription cofactor activity10851137
GO:0008134NAS-transcription factor binding17611704
GO:0046983IEA-protein dimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0006351IEA-transcription, DNA-templated-
GO:0006355TAS-regulation of transcription, DNA-templated10851137
GO:0007399IEA-nervous system development-
GO:0030154IEA-cell differentiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HES6CREBBP12068218160400 Affinity Capture-Western
HES6CREBBP10777718160400 Affinity Capture-Western
HES6TLE111294311551980 Affinity Capture-Western; Two-hybrid
HES6TLE112068211551980 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1859852
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030828-5'