Annotation Details for PRF1
Basic Information Top
| Gene Symbol: | PRF1 ( FLH2,HPLH2,MGC65093,P1,PFN1,PFP ) |
|---|---|
| Gene Full Name: | perforin 1 (pore forming protein) |
| Band: | 10q22.1 |
| Quick Links | Entrez ID:5551; OMIM: 170280; Uniprot ID:PERF_HUMAN; ENSEMBL ID: ENSG00000180644; HGNC ID: 9360 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005576 | IEA | - | extracellular region | - |
| GO:0005829 | IDA | - | cytosol | - |
| GO:0005886 | IEA | - | plasma membrane | - |
| GO:0016020 | IDA | - | membrane | 19946888 |
| GO:0016021 | IDA | - | integral component of membrane | 20889983 |
| GO:0031904 | IEA | - | endosome lumen | - |
| GO:0044194 | IDA | - | cytolytic granule | 9756476 |
| GO:0044194 | ISS | - | cytolytic granule | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005509 | ISS | - | calcium ion binding | - |
| GO:0005515 | IPI | - | protein binding | 11911826 |
| GO:0022829 | IDA | - | wide pore channel activity | 20889983 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0001771 | IDA | - | immunological synapse formation | 21438968 |
| GO:0002357 | ISS | - | defense response to tumor cell | - |
| GO:0002418 | ISS | - | immune response to tumor cell | - |
| GO:0006915 | TAS | - | apoptotic process | 10779745 |
| GO:0006968 | TAS | - | cellular defense response | 10779745 |
| GO:0019835 | ISS | - | cytolysis | - |
| GO:0051260 | IDA | - | protein homooligomerization | 20889983 |
| GO:0051607 | ISS | - | defense response to virus | - |
| GO:0051712 | IDA | - | positive regulation of killing of cells of other organism | 9756476 |
| GO:0055085 | IEA | - | transmembrane transport | - |
AlzGene, PDGene and SZGene