AutismKB 2.0

Annotation Details for SRGN


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SRGN ( FLJ12930,MGC9289,PPG,PRG,PRG1 )
Gene Full Name: serglycin
Band: 10q22.1
Quick LinksEntrez ID:5552; OMIM: 177040; Uniprot ID:SRGN_HUMAN; ENSEMBL ID: ENSG00000122862; HGNC ID: 9361
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139IEA-Golgi membrane-
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space11154222
GO:0005794IDA-Golgi apparatus15136585
GO:0031093TAS-platelet alpha granule lumen-
GO:0042588IEA-zymogen granule-
GO:0042629ISS-mast cell granule-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding11911826
GO:0005518IEA-collagen binding-
GO ID Evidence Qualifier GO_term References
GO:0002576TAS-platelet degranulation-
GO:0008626IDA-granzyme-mediated apoptotic signaling pathway11911826
GO:0016485ISS-protein processing-
GO:0030502IDA-negative regulation of bone mineralization16870619
GO:0031214IEA-biomineral tissue development-
GO:0033364ISS-mast cell secretory granule organization-
GO:0033368IBA-protease localization to mast cell secretory granule-
GO:0033371ISS-T cell secretory granule organization-
GO:0033373ISS-maintenance of protease location in mast cell secretory granule-
GO:0033382ISS-maintenance of granzyme B location in T cell secretory granule-
GO:0050710ISS-negative regulation of cytokine secretion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SRGNGZMB11154312388539 Reconstituted Complex
SRGNGZMB10925712388539 Reconstituted Complex
SGTASRGN11154316189514 Two-hybrid
SGTASRGN11234716189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
PRG1rs12437, rs7915745 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:97756
  • Data Attributes: HomoloGene calculated