Annotation Details for PRKACA
Basic Information Top
| Gene Symbol: | PRKACA ( MGC102831,MGC48865,PKACA ) |
|---|---|
| Gene Full Name: | protein kinase, cAMP-dependent, catalytic, alpha |
| Band: | 19p13.1 |
| Quick Links | Entrez ID:5566; OMIM: 601639; Uniprot ID:KAPCA_HUMAN; ENSEMBL ID: ENSG00000072062; HGNC ID: 9380 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0001669 | ISS | - | acrosomal vesicle | - |
| GO:0005634 | IDA | - | nucleus | 21085490 |
| GO:0005654 | TAS | - | nucleoplasm | - |
| GO:0005737 | IDA | - | cytoplasm | 21085490 |
| GO:0005739 | IEA | - | mitochondrion | - |
| GO:0005813 | IDA | - | centrosome | 21399614 |
| GO:0005829 | IDA | - | cytosol | - |
| GO:0005829 | TAS | - | cytosol | - |
| GO:0005952 | NAS | - | cAMP-dependent protein kinase complex | 2843813 |
| GO:0016020 | IDA | colocalizes_with | membrane | 15569306 |
| GO:0016607 | IDA | - | nuclear speck | 17594903 |
| GO:0031594 | IEA | - | neuromuscular junction | - |
| GO:0034704 | TAS | - | calcium channel complex | 23507255 |
| GO:0036126 | IEA | - | sperm flagellum | - |
| GO:0043197 | IEA | - | dendritic spine | - |
| GO:0044853 | IDA | - | plasma membrane raft | 17911601 |
| GO:0045171 | IDA | - | intercellular bridge | - |
| GO:0048471 | IDA | - | perinuclear region of cytoplasm | 21085490 |
| GO:0070062 | IDA | - | extracellular exosome | 23376485 |
| GO:0097546 | TAS | - | ciliary base | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0000287 | IEA | - | magnesium ion binding | - |
| GO:0004674 | EXP | - | protein serine/threonine kinase activity | 12628924 |
| GO:0004674 | IDA | - | protein serine/threonine kinase activity | 21085490 |
| GO:0004674 | IMP | - | protein serine/threonine kinase activity | 26537248 |
| GO:0004674 | TAS | - | protein serine/threonine kinase activity | - |
| GO:0004691 | IDA | - | cAMP-dependent protein kinase activity | 11029056 |
| GO:0004691 | ISS | - | cAMP-dependent protein kinase activity | - |
| GO:0004691 | NAS | - | cAMP-dependent protein kinase activity | 2843813 |
| GO:0004691 | TAS | - | cAMP-dependent protein kinase activity | - |
| GO:0004712 | IDA | - | protein serine/threonine/tyrosine kinase activity | 22797923 |
| GO:0005515 | IPI | - | protein binding | 11035810 |
| GO:0005524 | IEA | - | ATP binding | - |
| GO:0019901 | IPI | - | protein kinase binding | 11035810 |
| GO:0019904 | IEA | - | protein domain specific binding | - |
| GO:0030145 | IEA | - | manganese ion binding | - |
| GO:0031625 | IDA | - | ubiquitin protein ligase binding | 21423175 |
| GO:0034237 | IPI | - | protein kinase A regulatory subunit binding | 17911601 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0000086 | TAS | - | G2/M transition of mitotic cell cycle | - |
| GO:0001707 | IEA | - | mesoderm formation | - |
| GO:0001843 | IEA | - | neural tube closure | - |
| GO:0002027 | TAS | - | regulation of heart rate | 23507255 |
| GO:0002223 | TAS | - | stimulatory C-type lectin receptor signaling pathway | - |
| GO:0003091 | TAS | - | renal water homeostasis | - |
| GO:0006397 | IDA | - | mRNA processing | 17594903 |
| GO:0006468 | NAS | - | protein phosphorylation | 2843813 |
| GO:0007596 | TAS | - | blood coagulation | - |
| GO:0010881 | TAS | - | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | 23507255 |
| GO:0016241 | TAS | - | regulation of macroautophagy | 26046386 |
| GO:0018105 | IDA | - | peptidyl-serine phosphorylation | 10805756 |
| GO:0018105 | IMP | - | peptidyl-serine phosphorylation | 26537248 |
| GO:0018107 | IEA | - | peptidyl-threonine phosphorylation | - |
| GO:0034199 | TAS | - | activation of protein kinase A activity | - |
| GO:0034380 | TAS | - | high-density lipoprotein particle assembly | - |
| GO:0034605 | IDA | - | cellular response to heat | 21085490 |
| GO:0035584 | TAS | - | calcium-mediated signaling using intracellular calcium source | 23507255 |
| GO:0043393 | TAS | - | regulation of protein binding | 23507255 |
| GO:0045667 | IDA | - | regulation of osteoblast differentiation | 19949837 |
| GO:0046777 | IEA | - | protein autophosphorylation | - |
| GO:0046827 | IEA | - | positive regulation of protein export from nucleus | - |
| GO:0048240 | ISS | - | sperm capacitation | - |
| GO:0050804 | IEA | - | modulation of synaptic transmission | - |
| GO:0051480 | TAS | - | regulation of cytosolic calcium ion concentration | 23507255 |
| GO:0055117 | TAS | - | regulation of cardiac muscle contraction | 23507255 |
| GO:0060314 | TAS | - | regulation of ryanodine-sensitive calcium-release channel activity | 23507255 |
| GO:0061136 | IDA | - | regulation of proteasomal protein catabolic process | 17565987 |
| GO:0070613 | IEA | - | regulation of protein processing | - |
| GO:0071158 | ISS | - | positive regulation of cell cycle arrest | - |
| GO:0071333 | IDA | - | cellular response to glucose stimulus | 19949837 |
| GO:0071374 | IEA | - | cellular response to parathyroid hormone stimulus | - |
| GO:0071377 | TAS | - | cellular response to glucagon stimulus | - |
| GO:0071872 | TAS | - | cellular response to epinephrine stimulus | 23507255 |
| GO:0086064 | TAS | - | cell communication by electrical coupling involved in cardiac conduction | 23507255 |
| GO:0097711 | TAS | - | ciliary basal body docking | - |
| GO:1901621 | IEA | - | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | - |
| GO:1903779 | TAS | - | regulation of cardiac conduction | - |
| GO:2000810 | IDA | - | regulation of bicellular tight junction assembly | 15905176 |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| C11orf17 | PRKACA | 218042 | 15630084 | PRKACA interacts with AKIP1a. |
| No data |
AlzGene, PDGene and SZGene- MGI ID: MGI:97592
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-040801-208