AutismKB 2.0

Annotation Details for PRKAR2B


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Basic Information Top
Gene Symbol:PRKAR2B ( PRKAR2,RII-BETA )
Gene Full Name: protein kinase, cAMP-dependent, regulatory, type II, beta
Band: 7q22.3
Quick LinksEntrez ID:5577; OMIM: 176912; Uniprot ID:KAP3_HUMAN; ENSEMBL ID: ENSG00000005249; HGNC ID: 9392
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm21423175
GO:0005743IEA-mitochondrial inner membrane-
GO:0005813IDA-centrosome21399614
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane21423175
GO:0005952IEA-cAMP-dependent protein kinase complex-
GO:0043025IEA-neuronal cell body-
GO:0043197ISS-dendritic spine-
GO:0043198ISS-dendritic shaft-
GO:0045121IEA-membrane raft-
GO:0048471IEA-perinuclear region of cytoplasm-
GO:0070062IDA-extracellular exosome23533145
GO:0097546TAS-ciliary base-
GO ID Evidence Qualifier GO_term References
GO:0004862IDA-cAMP-dependent protein kinase inhibitor activity21812984
GO:0005515IPI-protein binding23455922
GO:0008603IDA-cAMP-dependent protein kinase regulator activity21812984
GO:0019904IEA-protein domain specific binding-
GO:0030552IEA-cAMP binding-
GO:0031625IDA-ubiquitin protein ligase binding21423175
GO:0034236IPI-protein kinase A catalytic subunit binding21812984
GO ID Evidence Qualifier GO_term References
GO:0000086TAS-G2/M transition of mitotic cell cycle-
GO:0003091TAS-renal water homeostasis-
GO:0006631IEA-fatty acid metabolic process-
GO:0007596TAS-blood coagulation-
GO:0007612IEA-learning-
GO:0034199TAS-activation of protein kinase A activity-
GO:0035556TAS-intracellular signal transduction2851102
GO:0071377TAS-cellular response to glucagon stimulus-
GO:0097332IEA-response to antipsychotic drug-
GO:0097338IEA-response to clozapine-
GO:0097711TAS-ciliary basal body docking-
GO:2000480IDA-negative regulation of cAMP-dependent protein kinase activity21812984
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
AKAP5PRKAR2B1148748509414 Reconstituted Complex
AKAP5PRKAR2B1115638509414 Reconstituted Complex
RYR2PRKAR2B11156310830164 Co-fractionation
RYR2PRKAR2B11217410830164 Co-fractionation
AKAP11PRKAR2B11638410864471 Affinity Capture-Western; Far Western
AKAP11PRKAR2B11156310864471 Affinity Capture-Western; Far Western
C3orf15PRKAR2B12463012223483 Reconstituted Complex
C3orf15PRKAR2B11156312223483 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97760
  • Data Attributes: MGI curated and HomoloGene calculated
No data