AutismKB 2.0

Annotation Details for SCN3B


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Basic Information Top
Gene Symbol:SCN3B ( HSA243396,SCNB3 )
Gene Full Name: sodium channel, voltage-gated, type III, beta
Band: 11q24.1
Quick LinksEntrez ID:55800; OMIM: 608214; Uniprot ID:SCN3B_HUMAN; ENSEMBL ID: ENSG00000166257; HGNC ID: 20665
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001518IDA-voltage-gated sodium channel complex20042427
GO:0001518TAS-voltage-gated sodium channel complex21895525
GO:0005886IDA-plasma membrane-
GO:0016021NAS-integral component of membrane10688874
GO:0030018ISS-Z disc-
GO ID Evidence Qualifier GO_term References
GO:0005248NAS-voltage-gated sodium channel activity10688874
GO:0017080IDA-sodium channel regulator activity20226894
GO:0017080IMP-sodium channel regulator activity20042427
GO:0044325IPI-ion channel binding20042427
GO:0086006IDA-voltage-gated sodium channel activity involved in cardiac muscle cell action potential20042427
GO:0086006IMP-voltage-gated sodium channel activity involved in cardiac muscle cell action potential21051419
GO ID Evidence Qualifier GO_term References
GO:0006814NAS-sodium ion transport10688874
GO:0007399IEA-nervous system development-
GO:0010460ISS-positive regulation of heart rate-
GO:0010765IDA-positive regulation of sodium ion transport20042427
GO:0010765IMP-positive regulation of sodium ion transport21051419
GO:0019233IEA-sensory perception of pain-
GO:0035725IDA-sodium ion transmembrane transport20042427
GO:0051899IDA-membrane depolarization21051419
GO:0060048IMP-cardiac muscle contraction20042427
GO:0060078IEA-regulation of postsynaptic membrane potential-
GO:0060371IMP-regulation of atrial cardiac muscle cell membrane depolarization21051419
GO:0060373IMP-regulation of ventricular cardiac muscle cell membrane depolarization20042427
GO:0072659IMP-protein localization to plasma membrane20042427
GO:0086002IMP-cardiac muscle cell action potential involved in contraction21051419
GO:0086005IMP-ventricular cardiac muscle cell action potential20042427
GO:0086010IDA-membrane depolarization during action potential20042427
GO:0086010IMP-membrane depolarization during action potential21051419
GO:0086012IMP-membrane depolarization during cardiac muscle cell action potential21051419
GO:0086014IMP-atrial cardiac muscle cell action potential21051419
GO:0086015ISS-SA node cell action potential-
GO:0086091IMP-regulation of heart rate by cardiac conduction20042427
GO:2000649IMP-regulation of sodium ion transmembrane transporter activity20042427
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1918882
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070920-2'