AutismKB 2.0

Annotation Details for KDM3A


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Basic Information Top
Gene Symbol:KDM3A ( DKFZp686A24246,DKFZp686P07111,JHDM2A,JHMD2A,JMJD1,JMJD1A,KIAA0742,TSGA )
Gene Full Name: lysine (K)-specific demethylase 3A
Band: 2p11.2
Quick LinksEntrez ID:55818; OMIM: 611512; Uniprot ID:KDM3A_HUMAN; ENSEMBL ID: ENSG00000115548; HGNC ID: 20815
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000785IBA-chromatin-
GO:0005634IDA-nucleus16603237
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005737IEA-cytoplasm-
GO:0016020IDA-membrane19946888
GO ID Evidence Qualifier GO_term References
GO:0000976IBA-transcription regulatory region sequence-specific DNA binding-
GO:0001047IEA-core promoter binding-
GO:0003700IEA-transcription factor activity, sequence-specific DNA binding-
GO:0005506IMP-iron ion binding16603237
GO:0031490IBA-chromatin DNA binding-
GO:0032452TAS-histone demethylase activity-
GO:0032454IBA-histone demethylase activity (H3-K9 specific)-
GO:0050681IDA-androgen receptor binding16603237
GO:0051213IEA-dioxygenase activity-
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0007290IEA-spermatid nucleus elongation-
GO:0009755IDA-hormone-mediated signaling pathway16603237
GO:0030521IDA-androgen receptor signaling pathway16603237
GO:0033169IDA-histone H3-K9 demethylation16603237
GO:0036123IEA-histone H3-K9 dimethylation-
GO:0045893IMP-positive regulation of transcription, DNA-templated16603237
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0046293IDA-formaldehyde biosynthetic process16603237
GO:0051573IEA-negative regulation of histone H3-K9 methylation-
GO:0055114IEA-oxidation-reduction process-
GO:2000036IEA-regulation of stem cell population maintenance-
GO:2000736IEA-regulation of stem cell differentiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
KDM3AETV212092716619273 Affinity Capture-Western; Reconstituted Complex
KDM3AETV210841716619273 Affinity Capture-Western; Reconstituted Complex
KDM3ATCEAL111474519615732 Affinity Capture-MS
KDM3ATCEAL112092719615732 Affinity Capture-MS
MKL2KDM3A12092717991879 Reconstituted Complex
MKL2KDM3A12156317991879 Reconstituted Complex
MKL1KDM3A12164217991879 Reconstituted Complex
MKL1KDM3A12092717991879 Reconstituted Complex
MYOCDKDM3A12504417991879 Reconstituted Complex
MYOCDKDM3A12092717991879 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98847
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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