AutismKB 2.0

Annotation Details for PRKCG


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Basic Information Top
Gene Symbol:PRKCG ( MGC57564,PKC-gamma,PKCC,PKCG,SCA14 )
Gene Full Name: protein kinase C, gamma
Band: 19q13.42
Quick LinksEntrez ID:5582; OMIM: 176980; Uniprot ID:KPCG_HUMAN; ENSEMBL ID: ENSG00000126583; HGNC ID: 9402
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IBA-intracellular-
GO:0005634IEA-nucleus-
GO:0005829ISS-cytosol-
GO:0005829TAS-cytosol-
GO:0005886ISS-plasma membrane-
GO:0005911IEA-cell-cell junction-
GO:0014069IEA-postsynaptic density-
GO:0030425ISS-dendrite-
GO:0048471ISS-perinuclear region of cytoplasm-
GO:0097060IEA-synaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0004672IDA-protein kinase activity15808853
GO:0004697TAS-protein kinase C activity3755548
GO:0004698TAS-calcium-dependent protein kinase C activity-
GO:0004712IDA-protein serine/threonine/tyrosine kinase activity22797923
GO:0005524IEA-ATP binding-
GO:0008270IEA-zinc ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006468TAS-protein phosphorylation3755548
GO:0007268IEA-chemical synaptic transmission-
GO:0007611IEA-learning or memory-
GO:0007635IEA-chemosensory behavior-
GO:0016310IDA-phosphorylation15808853
GO:0018105IBA-peptidyl-serine phosphorylation-
GO:0030168TAS-platelet activation-
GO:0031397IDA-negative regulation of protein ubiquitination15808853
GO:0032095ISS-regulation of response to food-
GO:0032425IDA-positive regulation of mismatch repair15808853
GO:0035556IBA-intracellular signal transduction-
GO:0042177IDA-negative regulation of protein catabolic process15808853
GO:0042752ISS-regulation of circadian rhythm-
GO:0043278ISS-response to morphine-
GO:0043524ISS-negative regulation of neuron apoptotic process-
GO:0046777IEA-protein autophosphorylation-
GO:0048265ISS-response to pain-
GO:0048511IEA-rhythmic process-
GO:0050764IEA-regulation of phagocytosis-
GO:0060384IEA-innervation-
GO:1901799ISS-negative regulation of proteasomal protein catabolic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PRKCGGABRA110882812091471 Affinity Capture-Western
PRKCGGABRA111156812091471 Affinity Capture-Western
PRKCGGABRA410883112091471 Affinity Capture-Western
PRKCGGABRA411156812091471 Affinity Capture-Western
PRKCGGRIA411156812471040 Affinity Capture-Western; Reconstituted Complex
PRKCGGRIA410915012471040 Affinity Capture-Western; Reconstituted Complex
TIAM1PRKCG11156810212259 Biochemical Activity
TIAM1PRKCG11293010212259 Biochemical Activity
YWHAGPRKCG11336410433554 Affinity Capture-Western
YWHAGPRKCG11156810433554 Affinity Capture-Western
RGS2PRKCG11192911063746 Biochemical Activity
RGS2PRKCG11156811063746 Biochemical Activity
AFAP1PRKCG12189512134071 Reconstituted Complex
AFAP1PRKCG11156812134071 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
PRKCGrs2242243, rs2242244, rs3745405 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
PRKCGrs307941, rs3745405, rs454006 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:97597
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-090206-1'