AutismKB 2.0

Annotation Details for PAG1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PAG1 ( CBP,FLJ37858,MGC138364,PAG )
Gene Full Name: phosphoprotein associated with glycosphingolipid microdomains 1
Band: 8q21.13
Quick LinksEntrez ID:55824; OMIM: 605767; Uniprot ID:PAG1_HUMAN; ENSEMBL ID: ENSG00000076641; HGNC ID: 30043
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886IDA-plasma membrane10790433
GO:0005886TAS-plasma membrane-
GO:0005887IBA-integral component of plasma membrane-
GO:0045121IDA-membrane raft10790433
GO ID Evidence Qualifier GO_term References
GO:0005068IBA-transmembrane receptor protein tyrosine kinase adaptor activity-
GO:0005070NAS-SH3/SH2 adaptor activity10790433
GO:0005515IPI-protein binding10790433
GO:0042169IDA-SH2 domain binding10790433
GO ID Evidence Qualifier GO_term References
GO:0002250IEA-adaptive immune response-
GO:0007165TAS-signal transduction10790433
GO:0007169IBA-transmembrane receptor protein tyrosine kinase signaling pathway-
GO:0007173TAS-epidermal growth factor receptor signaling pathway-
GO:0009967IEA-positive regulation of signal transduction-
GO:0035556IDA-intracellular signal transduction10790433
GO:0050852TAS-T cell receptor signaling pathway-
GO:0050863IDA-regulation of T cell activation10790433
GO:0050868IBA-negative regulation of T cell activation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PAG1ABL11065439334312 Affinity Capture-Western; Two-hybrid
PAG1ABL11209319334312 Affinity Capture-Western; Two-hybrid
PAG1CSK10783210790433 Affinity Capture-Western; Reconstituted Complex
PAG1CSK12093110790433 Affinity Capture-Western; Reconstituted Complex
PAG1FYN12093110790433 Affinity Capture-Western; Reconstituted Complex
PAG1FYN10881010790433 Affinity Capture-Western; Reconstituted Complex
PAG1GRB210914210790433 Reconstituted Complex
PAG1GRB212093110790433 Reconstituted Complex
PAG1LCK12093110790433 Reconstituted Complex
PAG1LCK11012410790433 Reconstituted Complex
PAG1LCP211012910790433 Reconstituted Complex
PAG1LCP212093110790433 Reconstituted Complex
PAG1LYN11024510790433 Reconstituted Complex
PAG1LYN12093110790433 Reconstituted Complex
PAG1PTPN611174210790433 Reconstituted Complex
PAG1PTPN612093110790433 Reconstituted Complex
PAG1SHC111236110790433 Reconstituted Complex
PAG1SHC112093110790433 Reconstituted Complex
PAG1SYK11271710790433 Reconstituted Complex
PAG1SYK12093110790433 Reconstituted Complex
PAG1VAV112093110790433 Reconstituted Complex
PAG1VAV111325210790433 Reconstituted Complex
PAG1ZAP7011336710790433 Reconstituted Complex
PAG1ZAP7012093110790433 Reconstituted Complex
PAG1SLC9A3R111476911684085 Affinity Capture-Western; Co-fractionation; Far Western; Two-hybrid
PAG1SLC9A3R112093111684085 Affinity Capture-Western; Co-fractionation; Far Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2443160
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved