AutismKB 2.0

Annotation Details for C3orf10


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Basic Information Top
Gene Symbol:C3orf10 ( MDS027,hHBrk1 )
Gene Full Name: chromosome 3 open reading frame 10
Band: 3p25.3
Quick LinksEntrez ID:55845; OMIM: 611183; Uniprot ID:BRK1_HUMAN; ENSEMBL ID: ; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005856IEA-cytoskeleton-
GO:0030027ISS-lamellipodium-
GO:0031209IDA-SCAR complex21107423
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding24439377
GO:0032403IDA-protein complex binding18560548
GO:0048365IDAcontributes_toRac GTPase binding21107423
GO ID Evidence Qualifier GO_term References
GO:0001701IEA-in utero embryonic development-
GO:0007015IEA-actin filament organization-
GO:0008284IEA-positive regulation of cell proliferation-
GO:0010592IMP-positive regulation of lamellipodium assembly18560548
GO:0016601IDA-Rac protein signal transduction21107423
GO:0038096TAS-Fc-gamma receptor signaling pathway involved in phagocytosis-
GO:0048010TAS-vascular endothelial growth factor receptor signaling pathway-
GO:0048870IBA-cell motility-
GO:0070207IDA-protein homotrimerization18560548
GO:2000601IDA-positive regulation of Arp2/3 complex-mediated actin nucleation21107423
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1915406
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018